557111-00-9

Upstream product

• 94022-99-8 3-(2-(trifluoromethyl)phenyl)propanoic acid 

Downstream Products

• 808169-99-5 N-(4-amino-2-benzoylphenyl)-3-(2-trifluoromethylphenyl)propionic acid amide 
• 808170-38-9 N-(2-benzoyl-4-nitrophenyl)-3-(2-trifluoromethylphenyl)propionic acid amide 

Relevant academic research and scientific papers

Rh(III)-Catalyzed meta-C-H Olefination Directed by a Nitrile Template

A range of Rh(III)-catalyzed ortho-C-H functionalizations have been developed; however, extension of this reactivity to remote C-H functionalizations through large-ring rhodacyclic intermediates has yet to be demonstrated. Herein we report the first examp

Pyrimidinedione derivative capable of inhibiting monocarboxylate transporter

The invention relates to a pyrimidinedione derivative capable of inhibiting a monocarboxylate transporter, the pyrimidinedione derivative is a formula (I) compound and/or a pharmaceutically acceptablesalt thereof, and/or a stereoisomer thereof, and/or a solvate thereof, the compound has the effect of inhibiting the activity of the monocarboxylate transporter, and also comprises a pharmaceutical composition containing the formula (I) compound and the use of the pharmaceutical composition in treatment.

Cross-coupling of remote meta -c-h bonds directed by a u-shaped template

meta-C-H arylation and methylation of 3-phenylpropanoic acid and phenolic derivatives were developed using an easily removable nitrile template. The combination of a weakly coordinating U-shaped template and mono-protected amino acid ligand was crucial fo

2-(Arylpropionylamino)- and 2-(arylacryloylamino)benzophenones: Farnesyltransferase inhibition and antimalarial activity

Structural variation of the 2-acylamino moiety of some benzophenone farnesyltransferase inhibitors led to the para-trifluoromethylphenylpropionyl derivative with relatively low farnesyltransferase inhibition but considerable antimalarial activity and no c