5572-41-8

Upstream product

• 4821-81-2 Z-L-Ala cyanomethyl ester 
• 141-43-5 ethanolamine 
• 1142-20-7 N-Cbz-Ala 
• 3401-36-3 (N-benzyloxycarbonyl)-L-alanine N-hydroxysuccinimide ester 
• 501-53-1 benzyl chloroformate 
• 6429-44-3 (S)-(-)-N-(benzyloxycarbonyl)alaninol 

Downstream Products

• 61280-93-1 N^α-Benzyloxycarbonyl-L-alanyl-L-alaninethanolamid 
• 61280-95-3 N^α-Benzyloxycarbonyl-D-alanyl-L-alaninethanolamid 
• 766479-72-5 (S)-2-Amino-N-(2-chloro-ethyl)-propionamide 
• 2503-31-3 N-benzyloxycarbonyl-L-alanylglycine 
• 34286-66-3 N-benzyloxycarbonyl-(R)alanyl-glycine 
• 4815-71-8 [(S)-1-(2-Chloro-ethylcarbamoyl)-ethyl]-carbamic acid benzyl ester 

Relevant academic research and scientific papers

Amino alcohols as C-Terminal Protecting Groups in Peptide Synthesis

The synthesis of peptides using amino alcohols as C-terminal protecting groups is described.C-Terminal protection of amino acid could be accomplished by reduction of the terminal carboxyl group to a hydroxymethyl group, and regeneration of the carboxyl group could be achieved by Jones' oxidation.This method was applied to the formation of di- and tripeptides.

Acylated sugar derivatives, processes for their manufacture, and their use

There are described sugar derivatives of the formula I STR1 that have immuno-stimulating action and that contain as inventive element at least one radical A1 or A2. These radicals A1 and A2, which may be constituents of the radicals R1, R2, R4, R6, R9, R10 or R12 according to formula I, are defined as follows: A1 represents lower alkanoyl that is substituted by aryl, heteroaryl or heteroarylthio and that may be additionally substituted by an ethylene radical which, with the above-mentioned aryl or heteroaryl substituent, forms a five-membered ring or represents ortho- or ortho/meta-substituted aroyl. A2 represents lower alkoxy substituted by aryl heteroaryl or heteroarylthio. Also described are processes for the manufacture of the compounds of the formula I and novel intermediates.