55751-60-5 Usage
Uses
Used in Pharmaceutical Industry:
2-(Cyclohexyloxy)-benzoic acid is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its chemical structure allows for modifications that can enhance the efficacy and properties of the resulting compounds.
Used in Organic Chemistry:
2-(Cyclohexyloxy)-benzoic acid is used as a versatile chemical intermediate in organic chemistry, facilitating the synthesis of a wide range of organic compounds. Its reactivity and functional groups make it a valuable component in the preparation of complex molecules and materials.
Used in Polymer Production:
2-(Cyclohexyloxy)-benzoic acid is used as a component in the production of polymers, where its unique structure can influence the properties of the resulting polymers. This can lead to the development of new materials with specific characteristics, such as improved strength, flexibility, or thermal stability.
Used in Industrial Applications:
2-(Cyclohexyloxy)-benzoic acid is used in various industrial applications, where its chemical properties can be harnessed for the production of a range of products. Its versatility in organic chemistry makes it a valuable asset in the development of new industrial processes and products.
Check Digit Verification of cas no
The CAS Registry Mumber 55751-60-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,7,5 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 55751-60:
(7*5)+(6*5)+(5*7)+(4*5)+(3*1)+(2*6)+(1*0)=135
135 % 10 = 5
So 55751-60-5 is a valid CAS Registry Number.
55751-60-5Relevant academic research and scientific papers
Design and synthesis of 6-fluoro-2-naphthyl derivatives as novel CCR3 antagonists with reduced CYP2D6 inhibition
Sato, Ippei,Morihira, Koichiro,Inami, Hiroshi,Kubota, Hirokazu,Morokata, Tatsuaki,Suzuki, Keiko,Iura, Yosuke,Nitta, Aiko,Imaoka, Takayuki,Takahashi, Toshiya,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-ichi
, p. 8607 - 8618 (2008/12/23)
In our previous study on discovering novel types of CCR3 antagonists, we found a fluoronaphthalene derivative (1) that exhibited potent CCR3 inhibitory activity with an IC50 value of 20 nM. However, compound 1 also inhibited human cytochrome P450 2D6 (CYP2D6) with an IC50 value of 400 nM. In order to reduce its CYP2D6 inhibitory activity, we performed further systematic structural modifications on 1. In particular, we focused on reducing the number of lipophilic moieties in the biphenyl part of 1, using C log D7.4 values as the reference index of lipophilicity. This research led to the identification of N-{(3-exo)-8-[(6-fluoro-2-naphthyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl}-3-(piperidin-1-ylcarbonyl)isonicotinamide 1-oxide (30) which showed comparable CCR3 inhibitory activity (IC50 = 23 nM) with much reduced CYP2D6 inhibitory activity (IC50 = 29,000 nM) compared with 1.
