55759-31-4Relevant academic research and scientific papers
Ti/Pd bimetallic systems for the efficient allylation of carbonyl compounds and homocoupling reactions
Millan, Alba,Campana, Araceli G.,Bazdi, Btissam,Miguel, Delia,Alvarez De Cienfuegos, Luis,Echavarren, Antonio M.,Cuerva, Juan M.
experimental part, p. 3985 - 3994 (2011/05/07)
The allylation, crotylation and prenylation of aldehydes and ketones with stable and easily handled allylic carbonates is promoted by a Ti/Pd catalytic system. This Ti/Pd bimetallic system is especially convenient for the allylation of ketones, which are infrequent substrates in other related protocols, and can be carried out intramolecularly to yield five- and six-membered cyclic products with good stereoselectivities. In addition, Ti/Pd-mediated reductions and Wuertz-type dimerisation reactions can be readily carried out from allyl carbonates and carboxylates.
