55764-37-9

Basic information

• Product Name: 2-methylpent-2-enoyl chloride
• Synonyms: 2-methylpent-2-enoyl chloride;2-Methyl-2-pentenoic acid chloride
• CAS NO: 55764-37-9
• Molecular Formula: C₆H₉ClO
• Molecular Weight: 132.58806
• EINECS: 259-803-1
• Mol File: 55764-37-9.mol
• Article Data: 27

Chemical Properties

• Boiling Point: 162.5°Cat760mmHg
• Flash Point: 57.5°C
• Appearance: /
• Density: 1.023g/cm³
• Vapor Pressure: 2.16mmHg at 25°C
• Refractive Index: 1.447
• CAS DataBase Reference: 2-methylpent-2-enoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylpent-2-enoyl chloride(55764-37-9)
• EPA Substance Registry System: 2-methylpent-2-enoyl chloride(55764-37-9)

Safety Data

• Hazardous Substances Data: 55764-37-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H9ClO/c1-3-4-5(2)6(7)8/h4H,3H2,1-2H3/b5-4+

Upstream product

• 16957-70-3 2-methylpent-2-enoic acid 
• 3142-72-1 2-methyl-2-pentenoic acid 
• 623-36-9 (E)-2-methylpent-2-enal 
• 146984-85-2 ethyl (E)-2-iodo-2-pentenoate 
• 55314-57-3 ethyl pent-2-ynoate 
• 1617-40-9 ethyl (E)-2-methyl-2-pentenoate 
• 1838-77-3 4-methyl-5-hexen-3-ol 
• 159999-59-4 2-(acetoxyethylmethyl)acrylic acid methyl ester 
• 133181-02-9 3-hydroxy-2-methylene-pentanoic acid methyl ester 
• 1567-14-2 methyl (2E)-2-methyl-2-pentenoate 

Downstream Products

• 80510-15-2 (+)-(1S)-1-methylbutyl (2E)-2-methylpent-2-enoate 
• 3168-90-9 1-(2-methylcyclopent-1-enyl)ethanone 
• 135773-71-6 (2R,3R)-3-Ethyl-2,3-dimethyl-3,4,5,6-tetrahydro-2H-pentalen-1-one 
• 90936-96-2 2,3-dihydro-2-ethyl-3-methyl-5-ethoxycarbonyl-6-phenyl-4-pyrone 
• 96623-45-9 2-methyl-4'-isopropyl-2-pentenoyl anilide 
• 1316008-82-8 (Z)-N-trityl-2-methyl-3-pentenamide 
• 1316008-83-9 (E)-N-trityl-2-methyl-2-pentenamide 
• 1242029-53-3 C₁₈H₂₃NO 
• 760197-72-6 2-methyl-pent-2-enoic acid 1-[hydroxy(diphenyl)methyl]-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 613672-55-2 trans-2-benzyl-3-ethyl-4-methylisoxazolidin-5-one 

Relevant articles and documents

Palladium-Catalyzed Regioselective C-H Functionalization/Annulation Reaction of Amides and Allylbenzenes for the Synthesis of Isoquinolinones and Pyridinones

A regioselective C-H functionalization/annulation reaction of N-sulfonyl amides and allylbenzenes through a palladium-catalyzed C(sp2)-H allylation/aminopalladation/β-H elimination/isomerization sequence has been reported. Various aryl and alkenyl carboxamides are found to be efficient substrates to construct isoquinolinones and pyridinones in up to 96% yield. Using ambient air as the terminal oxidant is another advantage regarding environmental friendliness and operational simplicity.

Synthesis of Succinimides via Intramolecular Alder-Ene Reaction of 1,6-Enynes

A novel and convenient method has been developed for the facile synthesis of functionalized succinimide derivatives via intramolecular Alder-ene reaction of 1,6-enynes. This reaction features mild and metal-free reaction conditions, which offers a green and efficient entry to synthetically important succinimide scaffolds. Preliminary mechanistic studies suggest that a diradical intermediate might be involved in this transformation.

Nucleophilic halo-michael addition under lewis-base activation

A simple and general conjugate nucleophilic halogenation is presented. The THTO/halosilane combination has shown the ability to act as a nucleophilic halide source in the conjugate addition to a variety of Michael acceptors. In addition, a straightforward diastereoselective halogen installation using α,β-unsaturated acyloxazolidinones as platforms has been developed.