55776-85-7Relevant academic research and scientific papers
Tricyclic compound derivatives useful in the treatment of neoplastic diseases, inflammatory disorders and immunomodulatory disorders
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Page/Page column 58, (2008/12/06)
Provided are compounds of the formula (I): or a stereoisomer, tautomer, salt, hydrate or prodrug thereof that modulate tyrosine kinase activity, compositions comprising the compounds and methods of their use.
Reactions of 1,2- and 1,3-amino-alcohols with imidate salts and with ortho esters
Butt, Mohammed I.,Neilson, Douglas G.,Watson, Kathleen M.,Zakir-Ullah
, p. 2328 - 2332 (2007/10/04)
ω-Hydroxy-N-substituted amidines have been shown to be the intermediates in the formation of 2-oxazolines and 5,6-dihydro-4H-1,3-oxazines from the reactions of imidates and 1,2- and 1,3-amino-alcohols respectively, 1,2- and 1,3-Amino-alcohols also react with ortho esters to give 2-oxazolines and 5,6-dihydro-4H-1,3-oxazines, but N-acylamino-alcohols give rise to oxazolidines with ortho esters.
