N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide is a compound that functions as a ROCK (Rho-associated protein kinase) inhibitor. It is characterized by its ability to inhibit the activity of ROCK, which is a family of serine/threonine protein kinases that play a crucial role in various cellular processes, including cell migration, adhesion, and contraction.
557782-81-7
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Basic information
- Product Name: N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide
- Synonyms: N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide;ZINC00881524;ZINC00881524 (ROCK inhibitor)
- CAS NO:557782-81-7
- Molecular Formula: C21H20N2O3S
- Molecular Weight: 380.4601
- EINECS: N/A
- Product Categories: N/A
- Mol File: 557782-81-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: 2-8°C
- Solubility: N/A
- CAS DataBase Reference: N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide(CAS DataBase Reference)
- NIST Chemistry Reference: N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide(557782-81-7)
- EPA Substance Registry System: N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide(557782-81-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 557782-81-7(Hazardous Substances Data)
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557782-81-7 Usage
Uses
Used in Pharmaceutical Industry:N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide is used as a pharmaceutical agent for the treatment of various diseases and conditions. Its primary application is as a ROCK inhibitor, which can help in managing and treating conditions associated with the overactivation of ROCK, such as hypertension, cardiovascular diseases, and certain types of cancer.
Used in Research and Development:
In the field of research and development, N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide serves as a valuable tool for studying the role of ROCK in cellular processes and disease progression. By inhibiting ROCK activity, researchers can gain insights into the molecular mechanisms underlying various diseases and identify potential therapeutic targets for drug development.
Used in Drug Delivery Systems:
Similar to gallotannin, N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide can also be incorporated into drug delivery systems to enhance its bioavailability, delivery, and therapeutic outcomes. By employing various organic and metallic nanoparticles as carriers, the compound can be more effectively targeted to specific cells or tissues, improving its overall efficacy and reducing potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 557782-81-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,5,7,7,8 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.Calculate Digit Verification of CAS Registry Number 557782-81:
(8*5)+(7*5)+(6*7)+(5*7)+(4*8)+(3*2)+(2*8)+(1*1)=207
207 % 10 = 7
So 557782-81-7 is a valid CAS Registry Number.
557782-81-7Upstream product
557782-81-7Downstream Products
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N-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide
