557785-63-4

Upstream product

• 557785-62-3 (2aS,4R,8bR)-1-Benzyl-5-benzyloxy-4-benzyloxymethyl-3-[(S)-3-(3-hydroxy-4-methoxy-5-methyl-phenyl)-2-methylamino-propionyl]-6,8-dimethoxy-7-methyl-2a,3,4,8b-tetrahydro-1H-1,3-diaza-cyclobuta[a]naphthalen-2-one 
• 557785-61-2 C₆₈H₇₅N₃O₁₀Si 
• 557785-67-8 1-benzyl-5-benzyloxy-4-benzyloxymethyl-6,8-dimethoxy-7-methyl-2-oxo-2,2a,4,8b-tetrahydro-1H-1,3-diaza-cyclobuta[a]naphthalene-3-carboxylic acid tert-butyl ester 
• 557785-55-4 (4R,5S)-3-[(2R,3S)-1-Benzyl-2-(5-benzyloxy-2,4-dimethoxy-3-methyl-phenyl)-4-oxo-azetidin-3-yl]-4,5-diphenyl-oxazolidin-2-one 
• 557785-59-8 1-benzyl-5-benzyloxy-4-benzyloxymethyl-6,8-dimethoxy-7-methyl-2a,3,4,8b-tetrahydro-1H-1,3-diaza-cyclobuta[a]naphthalen-2-one 
• 557785-60-1 {2-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-1-chlorocarbonyl-ethyl}-methyl-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 557785-66-7 1-benzyl-5-hydroxy-6,8-dimethoxy-7-methyl-2-oxo-2,2a,4,8b-tetrahydro-1H-1,3-diaza-cyclobuta[a]naphthalene-3,4-dicarboxylic acid 3-tert-butyl ester 4-methyl ester 
• 557785-58-7 1-benzyl-5-hydroxy-4-hydroxymethyl-6,8-dimethoxy-7-methyl-2-oxo-2,2a,4,8b-tetrahydro-1H-1,3-diaza-cyclobuta[a]naphthalene-3-carboxylic acid tert-butyl ester 
• 557785-56-5 (2aS,4S,8bR)-1-Benzyl-5-hydroxy-6,8-dimethoxy-7-methyl-2-oxo-1,2,2a,3,4,8b-hexahydro-1,3-diaza-cyclobuta[a]naphthalene-4-carboxylic acid methyl ester 
• 557785-57-6 (2aS,4R,8bR)-1-Benzyl-5-hydroxy-6,8-dimethoxy-7-methyl-2-oxo-1,2,2a,3,4,8b-hexahydro-1,3-diaza-cyclobuta[a]naphthalene-4-carboxylic acid methyl ester 
• 557785-65-6 (3S,4R)-3-Amino-1-benzyl-4-(5-hydroxy-2,4-dimethoxy-3-methyl-phenyl)-azetidin-2-one 
• 557785-64-5 Benzyl-[1-(5-benzyloxy-2,4-dimethoxy-3-methyl-phenyl)-meth-(E)-ylidene]-amine 
• 575444-10-9 3-[3-(tert-butyl-dimethyl-silanyloxy)-4-methoxy-5-methyl-phenyl]-2-[(9H-fluoren-9-ylmethoxycarbonyl)-methyl-amino]-propionic acid 
• 82622-02-4 5-(benzyloxy)-2,4-dimethoxy-3-methylbenzaldehyde 

Relevant academic research and scientific papers

Regioselectivity of Pictet-Spengler cyclization reactions to construct the pentacyclic frameworks of the ecteinascidin-saframycin class of tetrahydroisoquinoline antitumor antibiotics

The regiochemical outcome of Pictet-Spengler cyclization reactions directed toward the preparation of the pentacyclic core of the ecteinascidin class of antitumor antibiotics has been investigated on two different phenolic substrates. In one substrate, th

Synthetic studies on ecteinascidin-743: Constructing a versatile pentacyclic intermediate for the synthesis of ecteinascidins and saframycins

(Matrix presented) The asymmetric synthesis of a highly functionalized pentacyclic tetrahydroisoquinoline relevant to the ecteinascidin, saframycin, safracin, and renieramycin family of antitumor alkaloids is described.