55805-07-7Relevant academic research and scientific papers
Direct nucleophilic fluorination of carbonyl groups of benzophenones and benzils with Deoxofluor
Chang, Ying,Tewari, Amit,Adi, Avi-Izak,Bae, Chulsung
, p. 9837 - 9842 (2008/12/22)
The carbonyl groups of diaryl ketones and diaryl diketones were directly fluorinated with bis(2-methoxyethyl)aminosulfur trifluoride (Deoxofluor) under neat conditions to give the corresponding gem-difluorides and tetrafluorinated derivatives in moderate
gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride
Reddy, V. Prakash,Alleti, Ramesh,Perambuduru, Meher K.,Welz-Biermann, Urs,Buchholz, Herwig,Prakash, G. K. Surya
, p. 654 - 656 (2007/10/03)
2,2-Diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor and pyridinium polyhydrogen fluoride (PPHF) under mild conditions in moderate to good yields. The Royal Society of Chemistry 2005.
Elemental fluorine. Part 5. Reactions of 1,3-dithiolanes and thioglycosides with fluorine-iodine mixtures
Chambers, Richard D.,Sandford, Graham,Sparrowhawk, Matthew E.,Atherton, Malcolm J.
, p. 1941 - 1944 (2007/10/03)
1,3-Dithiolanes, prepared from diaryl ketones, react with elemental fluorine-iodine mixtures to give the corresponding difluoromethylene derivatives. Under the same conditions, thioglycosides give glycosyl fluorides in good yields. Reaction of 1,3-dithiolanes with fluorine in aqueous acetonitrile provides a remarkably mild method for efficient deprotection to the parent ketone.
The Conversion of Diaryl-1,3-Dithiolanes into gem-Difluoromethylene Compounds by a Combination of Elemental Fluorine and Iodine
Chambers, Richard D.,Sandford, Graham,Atherton, Malcolm
, p. 177 - 178 (2007/10/02)
Diaryl-1,3-dithiolanes are converted to gem-difluorides in good yield by reaction with a mixture of elemental fluorine and iodine in acetonitrile at room temperature.
