55805-20-4

Usage

Uses

Used in Pharmaceutical Industry:
3-Carboxy-alpha,alpha-difluorotoluene and 3-Carboxybenzal fluoride are used as intermediates in the synthesis of pharmaceuticals for their versatile reactivity and ability to participate in a variety of chemical reactions.
Used in Agrochemical Industry:
3-Carboxy-alpha,alpha-difluorotoluene and 3-Carboxybenzal fluoride are used as intermediates in the synthesis of agrochemicals for their versatile reactivity and ability to participate in a variety of chemical reactions.
Used in Fine Chemicals Industry:
3-Carboxy-alpha,alpha-difluorotoluene and 3-Carboxybenzal fluoride are used as intermediates in the synthesis of other fine chemicals for their versatile reactivity and ability to participate in a variety of chemical reactions.

Upstream product

• 55805-13-5 3-(difluoromethyl)benzonitrile 
• 99-04-7 m-Toluic acid 
• 52178-50-4 Methyl 3-formylbenzoate 
• 24964-64-5 3-Cyanobenzaldehyde 

Downstream Products

• 1402454-41-4 3-difluoromethyl-N-methoxy-N-methylbenzamide 
• 1056638-82-4 3-(difluoromethyl)benzoyl chloride 

Relevant academic research and scientific papers

Transition-metal-free C-H oxidative activation: Persulfate-promoted selective benzylic mono- and difluorination

An operationally simple and selective method for the direct conversion of benzylic C-H to C-F to obtain mono- and difluoromethylated arenes using Selectfluor as a fluorine source is developed. Persulfate can be used to selectively activate benzylic hydrogen atoms toward C-F bond formation without the aid of transition metal catalysts.

TETRAZOLINONE COMPOUND AND USE THEREOF

The compound represented by formula (1): wherein R4 and R5 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R6 represents a C1-C4 alkyl group, a C3-C6 cycloalkyl group, or the like; R7, R8, and R9 each represents a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group, or the like; R13 represents a C1-C3 alkyl group, or the like; and Q represents a phenyl group, or the like; has an excellent control effect on pests.

BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS

The present invention provides compounds of Formula (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.