55811-47-7

Upstream product

• 302338-15-4 2-((S)-1-[1,3]Dioxolan-2-yl-2,2-dimethyl-cyclopentyl)-ethylamine 
• 70030-18-1 2,2-dimethylcyclopentanecarboxaldehyde 
• 302338-13-2 (S)-2,2-Dimethyl-1-(2-nitro-ethyl)-cyclopentanecarbaldehyde 
• 325705-63-3 (S)-1-[2,2-Dimethyl-cyclopent-(E)-ylidenemethyl]-2-methoxymethyl-pyrrolidine 
• 302338-14-3 2-[(S)-2,2-Dimethyl-1-(2-nitro-ethyl)-cyclopentyl]-[1,3]dioxolane 

Relevant academic research and scientific papers

Enantioselective synthesis of polyzonimine and nitropolyzonamine, spirocyclic compounds from the defensive glands of a millipede, Polyzonium rosalbum

Asymmetric Michael addition of the enamine derived from 2,2-dimethylcyclopentanecarboxaldehyde and (S)-prolinol methyl ether to nitroethylene afforded the adduct of 76% ee, which finally yielded enantiomerically pure (+)-polyzonimine and (+)-nitropolyzonamine, compounds from the defensive glands of a millipede, Polyzonium rosalbum. The absolute configuration of (+)-polyzonimine was determined as S. (C) 2000 Elsevier Science Ltd.