55817-66-8

Basic information

• Product Name: 2-amino-1,4,5-triphenyl-pyrrole-3-carbonitrile
• Synonyms: 2-amino-1,4,5-triphenyl-pyrrole-3-carbonitrile
• CAS NO: 55817-66-8
• Molecular Formula: C₂₃H₁₇N₃
• Molecular Weight: 335.4
• Mol File: 55817-66-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 562°Cat760mmHg
• Flash Point: 293.7°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 1.17E-12mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 2-amino-1,4,5-triphenyl-pyrrole-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-1,4,5-triphenyl-pyrrole-3-carbonitrile(55817-66-8)
• EPA Substance Registry System: 2-amino-1,4,5-triphenyl-pyrrole-3-carbonitrile(55817-66-8)

Safety Data

• Hazardous Substances Data: 55817-66-8(Hazardous Substances Data)

Usage

Structure

Pyrrole derivative with three phenyl groups attached to the nitrogen atom and a cyano group attached to the carbon atom

Functional groups

Amino group at the 2-position of the pyrrole ring

Uses

Commonly used in organic synthesis and pharmaceutical research

Applications

Precursor for the development of new drugs and functional materials in medicinal chemistry and material science

InChI:InChI=1/C23H17N3/c24-16-20-21(17-10-4-1-5-11-17)22(18-12-6-2-7-13-18)26(23(20)25)19-14-8-3-9-15-19/h1-15H,25H2

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 5722-91-8 1,2-diphenyl-2-(phenylamino)ethanone 
• 109-77-3 malononitrile 
• 62-53-3 aniline 

Downstream Products

• 56344-47-9 5,6,7-triphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 
• 77373-48-9 2-Methyl-5,6,7-triphenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine 
• 144658-60-6 (E)-2-<(3-Cyano-1,4,5-triphenyl-1H-pyrrol-2-yl)amino>2-butendisaeuredimethylester 
• 144658-71-9 (Z)-2-<(3-Cyano-1,4,5-triphenyl-1H-pyrrol-2-yl)amino>2-butendisaeuredimethylester 

Relevant articles and documents

Synthesis and lung cancer cell line study of pyrrolo[2,3-d]pyrimidine analogs

Three series of new pyrrolo[2,3-d]pyrimidines having diverse groups at position C4 and N7 of the pyrrolo[2,3-d]pyrimidine core were synthesized and their cell line study on the National Cancer Institute (NCI) H1 299 lung cancer cell line was performed. The details of the synthetic methods and characterization data of the synthesized compounds have been presented in this study. Compounds 08a, 08h, 08j, 09h, 09i, 09j, 09m, 09n, and 09o showed excellent anticancer activity compared to standard doxorubicin half maximal inhibitory concentration value on NCI H1 299 (lung cancer cell line) which was nontoxic to normal Vero cell line.

Investigations about formation of a novel ring system: pyrrolo [2,3e] thiadiazine

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