55829-11-3Relevant academic research and scientific papers
α-Cyanobenzylpiperazines and a process for producing the same
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, (2008/06/13)
α-Cyanobenzylpiperazines represented by the formula SPC1 Or an acid addition salt thereof, wherein R1 is a halogen or 1-3C lower alkoxy, R2 and R3 are each hydrogen or 1-3C lower alkoxy, R4 is 1-3C lower alkyl,
Alpha-cyanoamine compounds and a process for producing the same
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, (2008/06/13)
α-Cyanoamine compounds represented by the following formula or an acid addition salt thereof SPC1 Wherein R1 is a halogen atom or lower alkoxy group, R2 and R3 are a hydrogen atom or lower alkoxy group, R4 is a hydrogen atom or lower alkyl group, R5 is a hydrogen atom, -COOR6 (R6 is lower alkyl group), SPC2 (R7 is lower alkoxy group, m is a numeral 0-3), --R8 --COOR9 (R8 is lower alkylene group, R9 is lower alkyl group), EQU1 (R10 and R11 are a hydrogen atom or lower alkyl group, or R10 and R11 jointly form alkylene group), or SPC3 (R1 to R4 are the same as defined above) and n is a numeral 2 or 3; but it is excluded when R5 is hydrogen atom or --COOR6 (R6 is the same as defined above) and n is a numeral 2, which are produced by reacting aromatic carbonyl compounds with piperazine or homopiperazine compounds in the pesence of hydrogen cyanide or salts thereof, or which are alternatively produced by reaction N-(α-cyanobenzyl)-piperazines of N-(α-cyanobenzyl)homopiperazines or acid addition salts thereof with halogenated compounds.
