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2-(4-nitrophenyl)-3-dimethylaminoprop-2-enenitrile is a chemical compound with the molecular formula C12H12N4O2. It is an organic nitrile derivative featuring a 4-nitrophenyl group attached to a 3-dimethylaminoprop-2-enenitrile moiety. 2-(4-nitrophenyl)-3-dimethylaminoprop-2-enenitrile is characterized by its yellow crystalline appearance and is soluble in organic solvents such as ethanol and acetone. It is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of herbicides and pesticides. Due to its reactivity and potential toxicity, it is essential to handle 2-(4-nitrophenyl)-3-dimethylaminoprop-2-enenitrile with care and in accordance with proper safety protocols.

5584-30-5

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5584-30-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5584-30-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,5,8 and 4 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5584-30:
(6*5)+(5*5)+(4*8)+(3*4)+(2*3)+(1*0)=105
105 % 10 = 5
So 5584-30-5 is a valid CAS Registry Number.

5584-30-5Relevant academic research and scientific papers

Studies with enamines: Route to aminoazolopyrimidines and arylazoazolopyrimidines

Salaheldin, Abdellatif M.,Khairou, Khalid S.

, p. 175 - 181 (2013/04/23)

An easy preparation of enaminonitrile derivatives and their transformation into new substituted azolopyrimidines is described. The one-step transformation was carried out under microwave irradiation and by classical heating methods. The use of microwave i

Enaminonitriles in heterocyclic synthesis: A route to 1,3-diaryl-4- Aminopyrazole derivatives

Medrasi, Hanadi Y.,Al-Sheikh, Mariam Abdullah,Salaheldin, Abdellatif Mohamed

, p. 535 - 544 (2013/03/13)

Benzylcyanide and 4-nitrobenzylcyanide condensed with triethyl orthoformate and piperidine or morpholine to yield 2-Aryl-2-piperidinyl or 2-morpholinylacrylonitriles. These coupled with aromatic diazonium salts to yield the 2-Arylhydrazno-2-Arylethane nit

New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck

Gommermann, Nina,Buehlmayer, Peter,Von Matt, Anette,Breitenstein, Werner,Masuya, Keiichi,Pirard, Bernard,Furet, Pascal,Cowan-Jacob, Sandra W.,Weckbecker, Gisbert

scheme or table, p. 3628 - 3631 (2010/09/04)

A novel series of pyrazolo[1,5a]pyrimidines was optimized to target lymphocyte-specific kinase (Lck). An efficient synthetic route was developed and SAR studies toward activity and selectivity are described, leading to Lck inhibitors with enzymatic, cellu

7-Aminopyrazolo[1,5-a]pyrimidines as potent multitargeted receptor tyrosine kinase inhibitors

Frey, Robin R.,Curtin, Michael L.,Albert, Daniel H.,Glaser, Keith B.,Pease, Lori J.,Soni, Niru B.,Bouska, Jennifer J.,Reuter, David,Stewart, Kent D.,Marcotte, Patrick,Bukofzer, Gail,Li, Junling,Davidsen, Steven K.,Michaelides, Michael R.

experimental part, p. 3777 - 3787 (2009/04/07)

7-Aminopyrazolo[1,5-a]pyrimidine urea receptor tyrosine kinase inhibitors have been discovered. Investigation of structure-activity relationships of the pyrazolo[1,5-a]pyrimidine nucleus led to a series of 6-(4-N,N′-diphenyl) ureas that potently inhibited

PYRAZOLO [1, 5-A] PYRIMIDINE DERIVATIVES AND THEIR THERAPEUTIC USE

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Page/Page column 8, (2008/06/13)

Disclosed are pyrazolo-pyrimidine derivatives which have interesting pharmaceutical properties.

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