558442-48-1

Upstream product

• 216769-56-1 (2E,4R)-4-(t-butoxycarbonylamino)-4-phenylbutenbutenoic acid methyl ester 

Downstream Products

• 558442-49-2 4-[(t-butoxycarbonyl)-amino]-4-phenylbutanol 
• 663956-47-6 (2RS,5R)-2-hydroxy-5-phenylpyrrolidine-1-carboxylic acid t-butyl ester 

Relevant academic research and scientific papers

NITROGEN-CONTAINING COMPOUNDS

A compound represented by formula (I); wherein ring A represents a nitrogen containing heterocyclic ring, ring B represents 5-membered heterocyclic ring which may have substituents, R represents a hydrogen atom or cyano and the other symbols represent as

Chemokine receptor binding heterocyclic compounds with enhanced efficacy

The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).