55862-98-1

Basic information

• Product Name: 1-(2,4,6-trimethylphenyl)-1H-pyrrole-2,5-dione
• Synonyms: 1H-pyrrole-2,5-dione, 1-(2,4,6-trimethylphenyl)-; 1-Mesityl-1H-pyrrole-2,5-dione
• CAS NO: 55862-98-1
• Molecular Formula: C₁₃H₁₃NO₂
• Molecular Weight: 215.2478
• Mol File: 55862-98-1.mol

Chemical Properties

• Boiling Point: 353°C at 760 mmHg
• Flash Point: 156.1°C
• Density: 1.201g/cm³
• Vapor Pressure: 3.7E-05mmHg at 25°C
• Refractive Index: 1.594
• CAS DataBase Reference: 1-(2,4,6-trimethylphenyl)-1H-pyrrole-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4,6-trimethylphenyl)-1H-pyrrole-2,5-dione(55862-98-1)
• EPA Substance Registry System: 1-(2,4,6-trimethylphenyl)-1H-pyrrole-2,5-dione(55862-98-1)

Safety Data

• Hazardous Substances Data: 55862-98-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Electronics:
1-(2,4,6-trimethylphenyl)-1H-pyrrole-2,5-dione is used as a component in organic electronics for its potential applications in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs). Its unique chemical structure and properties make it a promising candidate for enhancing the performance of these electronic devices and materials.
Used in Pharmaceutical Applications:
1-(2,4,6-trimethylphenyl)-1H-pyrrole-2,5-dione may be utilized as a pharmaceutical compound due to its interesting molecular structure and potential biological activity. Further research and development could reveal its use in the creation of new drugs or therapies.

Upstream product

• 88-05-1 2,4,6-trimethylaniline 
• 189875-67-0 C₁₃H₁₅NO₃ 

Downstream Products

• 113354-64-6 1,2,3,4-Tetrahydro-N-(2,4,6-trimethylphenyl)dibenzothiophen-2,3-dicarboximid 

Relevant articles and documents

Efficient method for the synthesis of functionalized basic maleimides

A three-step procedure involving Diels-Alder condensation of maleic anhydride with furane, formation of N-substituted imide upon reaction with appropriate diamine, and a final retro Diels-Alder regeneration of the maleic carbon-carbon double bond is proposed for an unequivocal synthesis of N-substituted basic maleimides. The novel method is characterized by mild reaction conditions, easy work-up, high yields, and no need for additional catalysis.

Chemical reactivity and antimicrobial activity of N-substituted maleimides

Several N-substituted maleimides containing substituents of varying bulkiness and polarity were synthesised and tested for antimicrobial and cytostatic activity. Neutral maleimides displayed relatively strong antifungal effect minimum inhibitory concentrations (MICs in the 0.54 g ml-1 range); their antibacterial activity was structure dependent and all were highly cytostatic, with IC50 values below 0.1 g ml-1. Low antimicrobial but high cytostatic activity was noted for basic maleimides containing tertiary aminoalkyl substituents. Chemical reactivity and lipophilicity influenced antibacterial activity of neutral maleimides but had little if any effect on their antifungal and cytostatic action. N-substituted maleimides affected biosynthesis of chitin and β(1,3)glucan, components of the fungal cell wall. The membrane enzyme, β(1,3)glucan synthase has been proposed as a putative primary target of N-ethylmaleimide and some of its analogues in Candida albicans cells.

N-phenyl maleic imides

Fungicidal compositions, optionally contain chlorinated N- (2,4,6-trimethhenyl)-maleic imides as active material. Such materials find use for controlling fungus disease in plants, especially in agriculture, viticulture, arboriculture, market-gardening an