55873-09-1 Usage
Uses
Used in Pharmaceutical Industry:
4(1H)-Pyrimidinone, 2-chloro(9CI) is used as a key intermediate in the synthesis of pyrazole derivatives, which are known for their antitumor properties. These pyrazole derivatives have the potential to be developed into effective drugs for the treatment of various types of cancer.
4(1H)-Pyrimidinone, 2-chloro(9CI)'s reactivity and structural features make it a versatile building block for the development of novel anticancer agents. By incorporating 4(1H)-Pyrimidinone, 2-chloro(9CI) into the molecular structure of pyrazole derivatives, researchers can explore new avenues for designing drugs with improved efficacy, selectivity, and reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 55873-09-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,8,7 and 3 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 55873-09:
(7*5)+(6*5)+(5*8)+(4*7)+(3*3)+(2*0)+(1*9)=151
151 % 10 = 1
So 55873-09-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H3ClN2O/c5-4-6-2-1-3(8)7-4/h1-2H,(H,6,7,8)
55873-09-1Relevant academic research and scientific papers
Syntheses of a triad of Flt3 kinase inhibitors: From bench to pilot plant
Shieh, Wen-Chung,Mckenna, Joe,Sclafani, Joseph A.,Xue, Song,Girgis, Michael,Vivelo, James,Radetich, Branko,Prasad, Kapa
, p. 1146 - 1155 (2013/01/03)
We have designed and developed an alternative synthesis for the manufacturing of a triad of Flt3 kinase inhibitors (AST487, ATH686, and AUZ454) to support clinical assessments of patients with Flt3-dependent tumor diseases. The new synthesis is convergent
Method for producing an optically active 1-substituted 2-propanol
-
, (2008/06/13)
A method for producing an optically active 1-substituted 2-propanol of the following formula 1, which comprises reacting a hydroxy aromatic compound of the following formula 2 with an optically active propylene oxide in the presence of a catalyst:AOH??Formula 2CH3C*H(OH)CH2OA??Formula 1wherein A is a univalent aromatic group, and C* is an asymmetric carbon atom.
