55883-90-4

Basic information

• Product Name: (METHYLTHIO)(MORPHOLIN-4-YL)METHYLENE]MALONONITRILE
• Synonyms: 2-[methylsulfanyl(morpholin-4-yl)methylidene]propanedinitrile
• CAS NO: 55883-90-4
• Molecular Formula: C₉H₁₁N₃OS
• Molecular Weight: 209.26814
• Mol File: 55883-90-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 318.7 °C at 760 mmHg
• Flash Point: 146.5 °C
• Appearance: /
• Density: 1.259 g/cm³
• Vapor Pressure: 0.000356mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: (METHYLTHIO)(MORPHOLIN-4-YL)METHYLENE]MALONONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (METHYLTHIO)(MORPHOLIN-4-YL)METHYLENE]MALONONITRILE(55883-90-4)
• EPA Substance Registry System: (METHYLTHIO)(MORPHOLIN-4-YL)METHYLENE]MALONONITRILE(55883-90-4)

Safety Data

• Hazardous Substances Data: 55883-90-4(Hazardous Substances Data)

Usage

General Description

(METHYLTHIO)(MORPHOLIN-4-YL)METHYLENE]MALONONITRILE is a chemical compound with the molecular formula C10H8N2S. It contains a malononitrile group, a morpholine ring, and a methylthio group. (METHYLTHIO)(MORPHOLIN-4-YL)METHYLENE]MALONONITRILE is commonly used in organic synthesis and pharmaceutical research as a building block for various complex molecules. It has been studied for its potential biological and pharmacological activities, with some research suggesting antibacterial and antitumor properties. However, due to its potential toxicity and reactivity, this compound should be handled with caution in laboratory settings.

InChI:InChI=1/C9H11N3OS/c1-14-9(8(6-10)7-11)12-2-4-13-5-3-12/h2-5H2,1H3

Upstream product

• 62604-08-4 4-morpholinecarbodithioic acid methyl ester 
• 3189-43-3 tetracyanoethylene oxide 
• 110-91-8 morpholine 
• 5147-80-8 [Bis(methylthio)methylene]malononitrile 

Relevant articles and documents

SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS NADPH OXIDASE INHIBITORS

The present application relates to substituted fused heteroaryl and heterocyclic compounds, useful as nicotinamide adenine dinucleotide phosphate oxidase inhibitors (NADPH oxidase inhibitors), processes for their preparation, pharmaceutical compositions comprising the compounds, and the use of the compounds or the compositions in the treatment or prevention of various diseases, conditions and/or disorders mediated by NADPH oxidase. (Formula I)

A one-pot, three-component, microwave-assisted synthesis of novel 7-amino-substituted 4-aminopyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles

The synthesis of novel 7-amino-substituted pyrazolo[1,5-a][1,3,5]triazine-8-carbonitriles was achieved via a three-component reaction of 3-amino-substituted 5-aminopyrazole-4-carbonitriles, cyanamide and triethyl orthoformate under microwave irradiation.

One-pot synthesis of new tetrasubstituted thiophenes and selenophenes

In this work, we described the synthesis of new tetrasubstituted thiophenes and selenophenes achieved by an easy one-pot four-step procedure. Expected compounds were obtained in good yield from ketene dithioacetals.