55919-60-3

Basic information

• Product Name: N-(2-cyanoethyl)-N-phenylnitrosamine
• Synonyms: N-(2-cyanoethyl)-N-phenylnitrosamine
• CAS NO: 55919-60-3
• Molecular Weight: 175.19
• Mol File: 55919-60-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-cyanoethyl)-N-phenylnitrosamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-cyanoethyl)-N-phenylnitrosamine(55919-60-3)
• EPA Substance Registry System: N-(2-cyanoethyl)-N-phenylnitrosamine(55919-60-3)

Safety Data

• Hazardous Substances Data: 55919-60-3(Hazardous Substances Data)

Upstream product

• 1075-76-9 N-cyanoethylaniline 
• 110-46-3 isopentyl nitrite 

Downstream Products

• 64359-09-7 1-(2-cyanoethyl)-3-methyl-2-phenylindole 

Relevant articles and documents

Rhodium(iii)-catalyzed indole synthesis at room temperature using the transient oxidizing directing group strategy

Rh-catalyzed reactions of N-alkyl anilines with internal alkynes at room temperature have been developed using an in situ generated N-nitroso group as a transient oxidizing directing group. Due to mild reaction conditions, this method enabled synthesis of a broad range of N-alkyl indoles, including even two indole-based medicinal compounds. Our work disclosed the feasibility of the transient oxidizing directing group strategy in C-H functionalization reactions, which possesses the potential to enhance overall step-economy and impart new reactivity patterns to substrates.