55944-71-3

Usage

Structure

A six-membered ring with five carbon atoms and one oxygen atom, a chlorinated heptyl group attached to the oxygen atom

+ Amphiphilic

Has both hydrophilic and hydrophobic parts, giving it surfactant and lubricant properties.

+ Building block

Used in organic synthesis reactions.

Safety precautions

Can cause irritation to skin, eyes, and respiratory tract. Handle with caution.

InChI:InChI=1/C12H23ClO2/c13-9-5-2-1-3-6-10-14-12-8-4-7-11-15-12/h12H,1-11H2

Upstream product

• 629-30-1 1,7-heptandiol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 55944-70-2 7-chloro-1-heptanol 

Downstream Products

• 70224-30-5 (R,Z)-14-methylhexadec-8-en-1-one 
• 70144-70-6 (R,E)-14-methyl-8-hexadecenal 

Relevant academic research and scientific papers

Ethynylation of the ether derivatives of ω-haloalkanols with lithium acetylide-ethylenediamide complex

A new operationally simple and highly efficient procedure for the ethynylation of ether derivatives of ω-haloalkanols with lithium acetylide-ethylenediamine complex in N,N-dimethylacetamide is described.

A simple approach to 12-azaprostaglandin congeners

The base-catalysed alkylation of N-acylated 3-pyrrolines has been studied.The reaction has been utilized in an approach to the synthesis of 12-azaprostaglandins according to the following sequence. 3-Pyrroline was acylated with 1-chloro-1-octen-3-one and the resulting amide alkylated at the 2-position with I-(CH2)6C(OCH3)3.Subsequently, the α- and β-(13,14-dihydro)-prostanoid chains were formed by sodium borohyride reduction, followed by hydrolysis.The resulting product, 1-(3-hydroxyoctyl)-2-(6-methoxycarbonylhexyl)-3-pyrroline (13), constitutes a central intermediate for 12-azaprostaglandins.