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Usage

Uses

Used in Organic Synthesis:
(E)-2,7-Dimethyl-3-octen-5-yne is used as a reagent in organic synthesis for its unique carbon-carbon triple bond, which allows for various chemical reactions and the formation of different compounds.
Used in Chemical Reactions:
(E)-2,7-Dimethyl-3-octen-5-yne is used as a building block in chemical reactions due to its linear structure and triple bond, enabling the creation of a wide range of specialty chemicals.
Used in Pharmaceutical Production:
(E)-2,7-Dimethyl-3-octen-5-yne is used as a key component in the production of various pharmaceuticals, taking advantage of its unique structure and reactivity.
Used in Medicinal Chemistry:
(E)-2,7-Dimethyl-3-octen-5-yne is used as a starting material in medicinal chemistry for the development of new drugs, given its biological activity and potential applications in the field.
Used in Pharmacology Research:
(E)-2,7-Dimethyl-3-octen-5-yne is used as a subject of pharmacological research to explore its potential therapeutic effects and applications in treating various medical conditions.

InChI:InChI=1/C10H16/c1-9(2)7-5-6-8-10(3)4/h5,7,9-10H,1-4H3/b7-5+

Upstream product

• 598-23-2 3-methyl-but-1-yne 
• 542-91-6 H₂SiEt₂ 
• 14813-68-4 1,4-diisopropyl-1,3-butadiyne 

Relevant academic research and scientific papers

Et2SiH2 assisted the selective dimerization of terminal alkynes catalyzed by Cp*2UMe2

A practical approach has been developed for the catalytic synthesis of short oligomers, dimers and/or trimers of terminal alkynes. The method allows control of the extent and, in some cases, the regiospecificity in the catalyzed oligomerization of terminal alkynes promoted by bis(pentamethylcyclopentadienyl)uranium dimethyl complex (Cp*2U(CH3)2, Cp= C5Me5). The metallocene precursor is known to promote the simultaneous production of a large number of differently sized oligomers in the presence of terminal alkynes. However, the addition of a specific secondary silane ensures the selective synthesis of short oligomers.

Controlling the catalytic oligomerization of terminal alkynes promoted by organoactinides: A strategy to short oligomers

A novel strategy has been developed for the catalytic synthesis of short oligomers, dimers and/or trimers, of terminal alkynes. The method allows control of the extent of and, in some cases, the regiospecificity in the catalyzed oligomerization of terminal alkynes promoted by bis(pentamethylcyclopentadienyl)actinide dimethyl complexes (Cp*2AnMe2; Cp* = C5Me5, An = Th, U). These metallocene precursors are known to promote the simultaneous production of a large number of differently sized oligomers in the presence of terminal alkynes. However, the addition of specific amines ensures the selective synthesis of short oligomers. Catalytic 'tailoring' to dimers or a mixture of dimers and trimers can be achieved by using nonbulky or bulky amines, respectively. The kinetics in the catalytic oligomerization of 1-hexyne, in the presence of i-BuNH2, mediated by Cp*2ThMe2 are first order in [alkyne], first order in [Th], and inverse first order in [amine]. Kinetic, spectroscopic, and mechanistic data argue that the turnover-limiting step involves the formation of the mono(amido)thorium acetylide complex with rapid insertion of the alkyne and protonolysis by the amine.