Indanol dehydrogenase, an enzyme within the oxidoreductase family, specifically targets the CH-OH group of donors with NAD+ or NADP+ as acceptors. It catalyzes the reversible oxidation of indanol to indanone, using NAD(P)+ as a cofactor. This enzyme is pivotal in the metabolism of aromatic compounds in certain bacteria and fungi, participating in the breakdown of aromatic ring structures. Additionally, it is a key enzyme in the biosynthesis of indole alkaloids, which are significant secondary metabolites with diverse biological activities. The study of indanol dehydrogenase and its biochemical properties offers potential applications in the biotechnology and pharmaceutical industries.
55976-95-9
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Basic information
- Product Name: indanol dehydrogenase
- Synonyms: indanol dehydrogenase;17-beta-hydroxysteroid dehydrogenase type 5;AKR1C3;aldo-keto reductase family 1 member C3;Prostaglandin F Synthase human;AKR1C3 human;DD3;DDX
- CAS NO:55976-95-9
- Molecular Formula:
- Molecular Weight:
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: ?70°C
- Solubility: N/A
- CAS DataBase Reference: indanol dehydrogenase(CAS DataBase Reference)
- NIST Chemistry Reference: indanol dehydrogenase(55976-95-9)
- EPA Substance Registry System: indanol dehydrogenase(55976-95-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 1
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 55976-95-9(Hazardous Substances Data)
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55976-95-9 Usage
Uses
Used in Biotechnology Industry:Indanol dehydrogenase is used as a biocatalyst for the synthesis of indole alkaloids, which are important secondary metabolites with various biological activities. Its ability to catalyze the reversible oxidation of indanol to indanone makes it a valuable tool in the production of these compounds.
Used in Pharmaceutical Industry:
Indanol dehydrogenase is employed as a target enzyme in the development of drugs that modulate the metabolism of aromatic compounds. Its role in the breakdown of aromatic ring structures in bacteria and fungi can be leveraged to create new therapeutic agents that target specific metabolic pathways.
Used in Metabolic Engineering:
Indanol dehydrogenase is utilized as a key enzyme in metabolic engineering efforts to optimize the production of indole alkaloids and other valuable secondary metabolites. By enhancing the activity or expression of this enzyme, researchers can improve the yield and efficiency of these compounds' biosynthesis.
Used in Environmental Biotechnology:
Indanol dehydrogenase is applied as a biocatalyst in the biodegradation of aromatic pollutants. Its ability to break down aromatic ring structures can be harnessed to develop bioremediation strategies for the treatment of contaminated environments.
Used in Synthetic Biology:
Indanol dehydrogenase is employed as a component in synthetic biological systems designed to produce novel compounds or enhance the production of existing ones. By integrating this enzyme into engineered metabolic pathways, researchers can create new biosynthetic routes for the generation of valuable chemicals or pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 55976-95-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,9,7 and 6 respectively; the second part has 2 digits, 9 and 5 respectively.Calculate Digit Verification of CAS Registry Number 55976-95:
(7*5)+(6*5)+(5*9)+(4*7)+(3*6)+(2*9)+(1*5)=179
179 % 10 = 9
So 55976-95-9 is a valid CAS Registry Number.
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indanol dehydrogenase
