Basic information

Product Name: OPHIOBOLIN B
Synonyms: OPHIOBOLIN B;3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al;Cochliobolin B;Cochliobolin B, Zizanin B, Ophiobolsin A
CAS NO:5601-74-1
Molecular Formula: C25H38O4
Molecular Weight: 402.57
EINECS: N/A
Product Categories: N/A
Mol File: 5601-74-1.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: OPHIOBOLIN B(CAS DataBase Reference)
NIST Chemistry Reference: OPHIOBOLIN B(5601-74-1)
EPA Substance Registry System: OPHIOBOLIN B(5601-74-1)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 5601-74-1(Hazardous Substances Data)

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Usage
SDS
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5601-74-1 Usage

Uses

Used in Anticancer Applications:
Ophiobolin B is used as an anticancer agent for inducing apoptosis in chronic lymphocytic leukemia cells with an LC50 value of 2 nM. It modulates several oncological signaling pathways, exerting inhibitory effects on tumor growth and progression.
Used in Antimicrobial Applications:
Ophiobolin B is used as an antimicrobial agent, exhibiting cytotoxic and antimicrobial effects against different zygomycetes with MIC values ranging from 25-50 μg/ml.
Used in Agricultural Industry:
Ophiobolin B is used as a fungal phytotoxin for inhibiting calmodulin, a protein involved in calcium regulation, which helps in controlling plant pathogenic fungi and protecting crops from diseases.
Used in Pharmaceutical Industry:
Ophiobolin B is used as a potential pharmaceutical candidate due to its ability to bind and irreversibly antagonize calmodulin, which can be utilized in the development of new drugs targeting various diseases and conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 5601-74-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,0 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5601-74:
(6*5)+(5*6)+(4*0)+(3*1)+(2*7)+(1*4)=81
81 % 10 = 1
So 5601-74-1 is a valid CAS Registry Number.

5601-74-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	OPHIOBOLIN B

1.2 Other means of identification

Product number	-
Other names	3,14-Dihydroxy-5-oxoophiobola-7,19-dien-25-al

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5601-74-1 SDS

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