56010-88-9 Usage
Uses
Used in Pharmaceutical Industry:
4-Methylpyrazole hydrochloride is used as a cytochrome P450 2E1 inhibitor for its ability to block the enzyme's activity, which is involved in the metabolism of various drugs and toxins. This inhibition can help reduce the risk of drug interactions and improve the safety and efficacy of certain medications.
Used in Research Applications:
In the field of research, 4-Methylpyrazole hydrochloride is used as a cytochrome P450 2E1 and alcohol dehydrogenase inhibitor in 1C11 neural progenitor cells. This application aids scientists in studying the effects of these enzymes on cellular processes and their potential role in various diseases.
Used in Alcohol Metabolism Studies:
4-Methylpyrazole hydrochloride is used to inhibit ethanol oxidation in VL-17A cells expressing alcohol dehydrogenase and HepG2 cells. This application is crucial for understanding the role of alcohol metabolism in liver function and the development of alcohol-related diseases.
Used in Toxicology Studies:
Due to its ability to inhibit cytochrome P450 2E1, 4-Methylpyrazole hydrochloride is also used in toxicology studies to investigate the effects of various toxins and their metabolites on the body. This can help researchers develop new strategies for detoxification and treatment of poisoning.
Biochem/physiol Actions
4-Methylpyrazole (4MP) inhibits ethanol oxidation in liver microsomes. It also blocks the c-Jun N-terminal kinase (JNK) activation in in vitro liver injury models.
Check Digit Verification of cas no
The CAS Registry Mumber 56010-88-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,0,1 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 56010-88:
(7*5)+(6*6)+(5*0)+(4*1)+(3*0)+(2*8)+(1*8)=99
99 % 10 = 9
So 56010-88-9 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2.ClH/c1-4-2-5-6-3-4;/h2-3H,1H3,(H,5,6);1H
