56030-19-4

Usage

Uses

Used in Pharmaceutical Research:
3-(3-FORMYLPHENYL)PROPANOIC ACID is used as a building block for the preparation of biologically active compounds, playing a crucial role in drug development. Its applications extend to the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other medicinal compounds, where its unique structure contributes to the therapeutic properties of the final products.
Used in Organic Synthesis:
In the realm of organic synthesis, 3-(3-FORMYLPHENYL)PROPANOIC ACID is utilized as an intermediate, facilitating the creation of a range of chemical products. Its versatility in forming different chemical entities makes it a valuable component in the synthesis of complex organic molecules.
Used in Fragrance and Flavoring Industry:
3-(3-FORMYLPHENYL)PROPANOIC ACID also finds application as an intermediate in the production of fragrances and flavoring agents. Its ability to contribute to the scent and taste profiles of various products makes it an important substance in the development of consumer goods in this industry.

Upstream product

• 626-19-7 Isophthalaldehyde 
• 74815-17-1 3-Formyl cinnamic acid 
• 110114-05-1 ethyl 3-(3-formylphenyl)propanoate 
• 62876-42-0 m-(Hydroxymethyl)-phenylpropionate 
• 3984-22-3 2-vinyl-1,3-dioxolane 
• 3132-99-8 m-bromobenzoic aldehyde 

Relevant academic research and scientific papers

IMMUNOPROTEASOME INHIBITORS

Provided herein are compounds, such as a compound of Formula (I), or a pharmaceutically acceptable salt thereof, that are immunoproteasome (such as LMP2 and LMP7) inhibitors. The compounds described herein can be useful for the treatment of diseases treatable by inhibition of immunoproteasomes. Also provided herein are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

Identification of a New Class of Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors Followed by a Structure-Activity Relationship Study

Screening of a small compound library at the three excitatory amino acid transporter subtypes 1-3 (EAAT1-3) resulted in the identification of compound (Z)-4-chloro-3-(5-((3-(2-ethoxy-2-oxoethyl)-2,4-dioxothiazolidin-5-ylidene)methyl)furan-2-yl)benzoic aci

Direct synthesis of 3-arylpropionic acids by tetraphosphine/palladium catalysed Heck reactions of aryl halides with acrolein ethylene acetal

Through the use of [PdCl(C3H5)]2/Cis,cis, cis-1,2,3,4-tetrakis(diphenylphosphinomethyl)cyclopentane as a catalyst, a range of aryl bromides undergoes Heck reaction with acrolein ethylene acetal. With this acetal, the selective formation of 3-arylpropionic acids/esters was observed. The functional group tolerance on the aryl halide is remarkable; substituents such as fluoro, methyl, methoxy, acetyl, formyl, benzoyl, nitro or nitrile are tolerated. Furthermore, this catalyst can be used at low loading, even for reactions of sterically hindered aryl bromides. Graphical Abstract.

4,5,6-Trinor-3,7-inter-m-phenylene prostaglandin F1α analogs

This invention is a group of 4,5,6-trinor-3,7-inter-m-phenylene prostaglandin-type compounds and processes for making them. These compounds are useful for a variety of pharmacological purposes, including hypotensive control and inhibition of platelet aggr

Bicyclo [3.1.0]hexane-3-one derivatives of 11-deoxy PGE

This invention is a group of 4,5,6-trinor-3,7-inter-m-phenylene prostaglandin-type compounds and processes for making them. These compounds are useful for a variety of pharmacological purposes, including hypotensive control and inhibition of platelet aggr

Tricyclic prostaglandin

Process for preparing bicyclic diols of the formula STR1 wherein Cp H2p is a valence bond or alkylene of one to 4 carbon atoms, inclusive, with one or 2 carbon atoms in the chain between the phenylene ring and --O--; wherein Y is a h