56030-32-1Relevant academic research and scientific papers
Nickel(II) complexes with amide ligands: Oxidative dehydrogenation of the amines in a tetradentate diamide-diamine ligand
Weeks, Colin L.,Turner, Peter,Fenton, Ronald R.,Lay, Peter A.
, p. 931 - 940 (2002)
Four complexes were prepared by the reaction of Ni(II) with three pyrrolidine based diamide-diamine ligands. The two amine groups in the ligand N,N′-bis(S-prolyl)-1,2-ethanediamine (S,S-bprolenH2) were oxidatively dehydrogenated during the prep
A comprehensive study on the effect of acid additives in 1( R),2( R)-Bis[(S)-prolinamido]cyclohexane catalyzed direct asymmetric aldol reactions in aqueous media
Bhowmick, Sudipto,Kunte, Sunita S.,Bhowmick, Kartick C.
, p. 84 - 92 (2015/01/30)
The catalytic efficacy of (1R,2 R)-bis[(S)-prolinamido]cyclohexane 1, prepared from the readily available natural amino acid L-proline has been studied for the direct asymmetric aldol reaction of cyclohexanone with substituted benzaldehydes at room temper
C2-symmetric proline-derived tetraamine as highly effective catalyst for direct asymmetric Michael addition of ketones to chalcones
Ma, Shijun,Wu, Lulu,Liu, Ming,Wang, Yongmei
experimental part, p. 3721 - 3729 (2012/05/20)
A C2-symmetric tetraamine catalyst was developed for the asymmetric Michael addition of ketones to chalcones. The corresponding adducts 1,5-dicarbonyl compounds were obtained in good chemical yields with high levels of diastereo- and enantioselectivities (up to >99:1 dr and 93% ee) under mild conditions. By studying the ESI-MS of the intermediates, a proposed mechanism was disclosed.
Chiral bisformamides as effective organocatalysts for the asymmetric one-pot, three-component strecker reaction
Wen, Yuehong,Xiong, Yan,Chang, Lu,Huang, Jinglun,Liu, Xiaohua,Feng, Xiaoming
, p. 7715 - 7719 (2008/02/12)
(Chemical Equation Presented) C2-symmetric chiral bisformamides have been shown to catalyze the asymmetric one-pot, three-component Strecker reaction, which produced the α-amino nitriles in excellent yields (up to 99%) with good enantioselectiv
Enantioselective cyanosilylation of ketones catalyzed by a nitrogen-containing bifunctional catalyst
Xiong, Yan,Huang, Xiao,Gou, Shaohua,Huang, Jinglun,Wen, Yuehong,Feng, Xiaoming
, p. 538 - 544 (2007/10/03)
An efficient and optically active, bifunctional tetraaza ligand (2S)-N-{(1R,2R)-2-[(S)-pyrrolidine-2-carboxamido]-1,2-diphenylethyl} pyrrolidine-2-carboxamide has been developed for the addition of trimethylsilyl cyanide (TMSCN) to ketones. The bifunctional catalyst system based on a monometallic titanium complex was found to be a highly enantioselective catalyst to provide O-TMS cyanohydrins with up to 94% ee. A possible transition state has been proposed to explain the origin of the activation and asymmetric inductivity.
Asymmetric cyanosilylation of aldehydes catalyzed by novel chiral tetraaza-titanium complexes
Liu, Yanling,Liu, Xiaohua,Xin, Junguo,Feng, Xiaoming
, p. 1085 - 1089 (2007/10/03)
The asymmetric addition of trimethylsilyl cyanide (TMSCN) to a range of aldehydes was efficiently catalyzed by a novel, easily prepared C 2-symmetric chiral tetraaza-Ti(IV) complex in high yields with up to 92% ee under mild conditions. A negative nonlinear effect between the ee of the ligand and the ee of the product was observed. Georg Thieme Verlag Stuttgart.
