56041-26-0

Upstream product

• 17972-14-4 N-(3,4-dimethoxybenzylidene)methanamine 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 123-08-0 4-hydroxy-benzaldehyde 
• 7306-46-9 4-chloromethyl-1,2-dimethoxy-benzene 
• 93-03-8 (3,4-dimethoxyphenyl)methanol 
• 10031-82-0 4-ethoxybenzaldehyde 
• 63368-34-3 (3,4-dimethoxybenzyl)triphenylphosphonium chloride 
• 126508-26-7 C₉H₁₁ClMgO 
• 56041-07-7 [1-(3,4-Dimethoxy-phenyl)-2-(4-ethoxy-phenyl)-ethyl]-methyl-amine 
• 56041-13-5 (2,2-Dimethoxy-ethyl)-[1-(3,4-dimethoxy-phenyl)-2-(4-ethoxy-phenyl)-ethyl]-methyl-amine 

Relevant academic research and scientific papers

In vitro study and structure-activity relationship analysis of stilbenoid derivatives as powerful vasorelaxants: Discovery of new lead compound

The development of vasorelaxant as the antihypertensive drug is important as it produces a rapid and direct relaxation effect on the blood vessel muscles. Resveratrol (RV), as the most widely studied stilbenoid and the lead compound, inducing the excellent vasorelaxation effect through the multiple signalling pathways. In this study, the in vitro vascular response of the synthesized trans-stilbenoid derivatives, SB 1-8e were primarily evaluated by employing the phenylephrine (PE)-precontracted endothelium-intact isolated aortic rings. Herein we report trans-3,4,4′-trihydroxystilbene (SB 8b) exhibited surprisingly more than 2-fold improvement to the maximal relaxation (Rmax) of RV. This article also highlights the characterization of the aromatic protons in terms of their unique splitting patterns in 1H NMR.

Anticancer Evaluation of 3,4,5,4'-trans-tetramethoxystilbene (DMU-212) and Its Analogs Against an Extensive Panel of Human Tumor Cell Lines

DMU-212, a methoxylated resveratrol analog, has significant anticancer activity, and selectively targets tumor cells. A library of E-diarylstilbenes structurally related to DMU-212 has been synthesized and evaluated for anticancer activity against a large