56041-77-1Relevant academic research and scientific papers
Cu(ii)-Catalyzed asymmetric boron conjugate addition to α,β-unsaturated imines in water
Kitanosono, Taku,Xu, Pengyu,Isshiki, Satoshi,Zhu, Lei,Kobayashi, Shu
supporting information, p. 9336 - 9339 (2014/08/05)
Enantioselective conjugate addition of bis(pinacolato)diboron to α,β-unsaturated imines proceeds smoothly in water in the presence of a chiral copper(ii) complex consisting of Cu(OAc)2 and chiral 2,2′-bipyridine. The corresponding β-boryl imines, which were oxidized to β-hydroxy imines, further leading to γ-amino alcohols, were obtained in high yields and high enantioselectivities.
Catalytic 1,3-difunctionalisation of organic backbones through a highly stereoselective, one-pot, boron conjugate-addition/reduction/oxidation process
Sole, Cristina,Tatla, Amolak,Mata, Jose A.,Whiting, Andrew,Gulyas, Henrik,Fernandez, Elena
supporting information; experimental part, p. 14248 - 14257 (2012/01/19)
A simple one-pot, three-step synthetic route to chiral 1,3-amino alcohols and 1,3-diols has been established. Considering the overall stereocontrol of the synthetic protocol, the first and key step is an enantioselective β-boration of α,β-unsaturated imin
