56046-85-6 Usage
Description
3,6-dichloro-9-(2-sulphonatophenyl)xanthylium, also known as SNAFL-2, is a fluorescent dye that is widely utilized in biological research and imaging applications. It is a xanthylium derivative characterized by the presence of two chlorine atoms at the 3 and 6 positions on the xanthene ring, and a sulphonatophenyl group at the 9 position. SNAFL-2 is particularly noted for its pH-sensitive fluorescence properties, which render it an indispensable tool for tracking intracellular pH changes in living cells. Furthermore, its applications extend to the study of calcium signaling and membrane potential changes across various biological systems. The distinctive chemical structure and properties of SNAFL-2 have solidified its role as a valuable asset in fluorescence microscopy and cellular imaging.
Uses
Used in Biological Research and Imaging Applications:
3,6-dichloro-9-(2-sulphonatophenyl)xanthylium is used as a fluorescent dye for its pH-sensitive fluorescence properties, allowing researchers to monitor intracellular pH changes in living cells. This capability is crucial for understanding cellular processes and dynamics that are influenced by pH variations.
Used in Cellular Imaging:
In the field of cellular imaging, 3,6-dichloro-9-(2-sulphonatophenyl)xanthylium serves as a vital tool for visualizing cellular structures and functions. Its fluorescence properties enable the detailed observation of cellular components and the analysis of their interactions within the complex cellular environment.
Used in Studying Calcium Signaling:
3,6-dichloro-9-(2-sulphonatophenyl)xanthylium is employed as a probe in the study of calcium signaling, a critical process in various cellular functions. Its sensitivity to pH changes aids in the detection and analysis of calcium ions' role in signal transduction pathways.
Used in Investigating Membrane Potential Changes:
In the study of membrane potential changes, 3,6-dichloro-9-(2-sulphonatophenyl)xanthylium is utilized to examine the electrical potential across cell membranes. This is important for understanding how cells communicate and respond to stimuli, as well as for probing the mechanisms of ion channels and transporters.
Used in Fluorescence Microscopy:
3,6-dichloro-9-(2-sulphonatophenyl)xanthylium is applied in fluorescence microscopy as a fluorescent marker. Its properties make it suitable for high-resolution imaging of cellular and subcellular structures, facilitating the study of biological processes at the microscopic level.
Check Digit Verification of cas no
The CAS Registry Mumber 56046-85-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,0,4 and 6 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 56046-85:
(7*5)+(6*6)+(5*0)+(4*4)+(3*6)+(2*8)+(1*5)=126
126 % 10 = 6
So 56046-85-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H10Cl2O4S/c20-11-5-7-13-16(9-11)25-17-10-12(21)6-8-14(17)19(13)15-3-1-2-4-18(15)26(22,23)24/h1-10H
