56073-95-1 Usage
Uses
Used in Pharmaceutical Industry:
[5-[[4-(Acetylamino)phenyl]thio]-1H-benzimidazol-2-yl]-carbamic acidmethylester is used as a potential pharmaceutical compound for its structural similarity to other bioactive molecules, which may indicate possible therapeutic applications. Further research is needed to explore its efficacy and safety in treating specific medical conditions.
Used in Research and Development:
In the field of chemical research and development, [5-[[4-(Acetylamino)phenyl]thio]-1H-benzimidazol-2-yl]-carbamic acidmethylester serves as a valuable compound for studying its chemical properties, reactivity, and potential interactions with biological systems. This research could lead to the discovery of new drugs or therapeutic approaches.
Used in Drug Design and Synthesis:
[5-[[4-(Acetylamino)phenyl]thio]-1H-benzimidazol-2-yl]-carbamic acidmethylester is used as a building block or template in drug design and synthesis, owing to its unique structural features. It may be modified or combined with other molecules to create new pharmaceutical agents with improved efficacy and selectivity for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 56073-95-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,0,7 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 56073-95:
(7*5)+(6*6)+(5*0)+(4*7)+(3*3)+(2*9)+(1*5)=131
131 % 10 = 1
So 56073-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H16N4O3S/c1-10(22)18-11-3-5-12(6-4-11)25-13-7-8-14-15(9-13)20-16(19-14)21-17(23)24-2/h3-9H,1-2H3,(H,18,22)(H2,19,20,21,23)
56073-95-1Relevant academic research and scientific papers
Discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors
Hasegawa, Masaichi,Nishigaki, Naohiko,Washio, Yoshiaki,Kano, Kazuya,Harris, Philip A.,Sato, Hideyuki,Mori, Ichiro,West, Rob I.,Shibahara, Megumi,Toyoda, Hiroko,Wang, Liping,Nolte, Robert T.,Veal, James M.,Cheung, Mui
, p. 4453 - 4470 (2008/02/13)
We herein disclose a novel chemical series of benzimidazole-ureas as inhibitors of VEGFR-2 and TIE-2 kinase receptors, both of which are implicated in angiogenesis. Structure-activity relationship (SAR) studies elucidated a critical role for the N1 nitrogen of both the benzimidazole (segment E) and urea (segment B) moieties. The SAR results were also supported by the X-ray crystallographic elucidation of the role of the N1 nitrogen and the urea moiety when the benzimidazole-urea compounds were bound to the VEGFR-2 enzyme. The left side phenyl ring (segment A) occupies the backpocket where a 3-hydrophobic substituent was favored for TIE-2 activity.
Syntheses and Anthelmintic Activity of 2-Substituted 5(6)-Arylthio- and 5(6)-Arylsulphono-benzimidazoles
Abuzar, Syed,Rao, K. V. B.,Sharma, Satyavan,Gupta, Suman,Katiyar, J. C.
, p. 178 - 181 (2007/10/02)
A series of 2-substituted 5(6)-arylthio- and 5(6)-arylsulphono-benzimidazoles (7-32) have been prepared and tested for their anthelmintic activity.Among the compounds tested against Hymenolepis nana infection in rats and mice and Ancylostoma ceylanicum in
