561017-41-2

Upstream product

• 561017-47-8 8β-tert-butyldimethylsilyloxy-25-methoxymethyloxy-de-A,B-11α,12α-epoxycholestan-9α-yl-methanesulfonate 
• 561017-31-0 8β-tert-butyldimethylsilyloxy-25-methoxymethyloxy-de-A,B-cholestan-12α-ol 
• 561017-36-5 8β-tert-butyldimethylsilyloxy-25-methoxymethyloxy-de-A,B-9α,11α-epoxycholestane 
• 561017-40-1 8β-tert-butyldimethylsilyloxy-25-methoxymethyloxy-de-A,B-cholest-9(11)-en-12α-ol 
• 561017-38-7 8β-tert-butyldimethylsilyloxy-25-methoxymethyloxy-de-A,B-cholest-11-en-9α-ol 
• 561017-34-3 8β-tert-butyldimethylsilyloxy-25-methoxymethyloxy-de-A,B-cholest-9(11)-ene 
• 561017-49-0 25-methoxymethyloxy-de-A,B-cholestane-8β,12α-diol 
• 561017-51-4 12α-hydroxy-25-methoxymethyloxy-de-A,B-cholestane-8-one 
• 561017-43-4 25-methoxymethyloxy-de-A,B-cholest-9(11)-en-8β-ol 
• 139619-76-4 (1R,3aR,7aR)-1-((R)-5-Methoxymethoxy-1,5-dimethyl-hexyl)-7a-methyl-1,2,3,3a,7,7a-hexahydro-inden-4-one 
• 81522-68-1 [(2Z)-2-[(3S,5R)-3,5-bis(tert-butyldimethylsilanyloxy)-2-methylenecyclohexylidene]ethyl]diphenylphosphine oxide 
• 561017-29-6 25-methoxymethyloxy-12α-trimethylsilyloxy-de-A,B-cholestane-8-one 
• 561017-45-6 8β-tert-butyldimethylsilyloxy-25-methoxymethyloxy-de-A,B-11α,12α-epoxycholestan-9α-ol 

Relevant academic research and scientific papers

Functionalization at C-12 of 1α,25-dihydroxyvitamin D3 strongly modulates the affinity for the vitamin D receptor (VDR)

(Matrix presented) The first synthesis of analogues of the natural hormone 1α,25-dihydroxyvitamin D3 (1a) with substituents at C-12 is reported. The following are the relative affinities of the novel compounds for the vitamin D receptor (VDR) c