56108-27-1

Basic information

• Product Name: 1-BENZYL-4-HYDROXY-4-(3-TRIFLUOROTOLYL)PIPERIDINOL
• Synonyms: 1-BENZYL-4-HYDROXY-4-(3-TRIFLUOROTOLYL)PIPERIDINOL;1-BENZYL-4-HYDROXY-4-(3-TRIDLUOROTOLYL)PIPERIDINOL;1-(Phenylmethyl)-4-(3-(trifluoromethyl)phenyl)-4-piperidinol;1-Benzyl-4-hydroxy-4-(3-trifluorotolyl)pi-peridine;1-Benzyl-4-（3-trifuoromethyl)-phenyl-4-piperdinol;1-Benzyl-4-(3-(trifluoromethyl)phenyl)piperidin-4-ol;N-Benzyl-4-（3-trifuoromethyl)-phenyl-4-piperidinol;1-Benzyl-4-(3-trifluoromethyl)phenyl-4-piperdinol
• CAS NO: 56108-27-1
• Molecular Formula: C₁₉H₂₀F₃NO
• Molecular Weight: 335.37
• Mol File: 56108-27-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 486.724 °C at 760 mmHg
• Flash Point: 248.162 °C
• Appearance: /
• Density: 1.345 g/cm³
• CAS DataBase Reference: 1-BENZYL-4-HYDROXY-4-(3-TRIFLUOROTOLYL)PIPERIDINOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-4-HYDROXY-4-(3-TRIFLUOROTOLYL)PIPERIDINOL(56108-27-1)
• EPA Substance Registry System: 1-BENZYL-4-HYDROXY-4-(3-TRIFLUOROTOLYL)PIPERIDINOL(56108-27-1)

Safety Data

• Hazardous Substances Data: 56108-27-1(Hazardous Substances Data)

Usage

General Description

1-BENZYL-4-HYDROXY-4-(3-TRIFLUOROTOLYL)PIPERIDINOL is a chemical compound consisting of a benzyl group and a piperidinol group with a hydroxy and trifluorotolyl substitution. 1-BENZYL-4-HYDROXY-4-(3-TRIFLUOROTOLYL)PIPERIDINOL is primarily used in research and development as a pharmaceutical intermediate in the synthesis of various medications. It is also used in the development of potential treatments for conditions such as depression and anxiety. Additionally, it has been studied for its potential applications in the development of new psychoactive substances and as a precursor to other chemical compounds. The specific properties, uses, and potential hazards of this compound should be carefully evaluated and considered in any research or application.

Upstream product

• 2249-28-7 4-(3-trifluoromethylphenyl)-4-hydroxy piperidine 
• 100-39-0 benzyl bromide 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 401-78-5 3-bromo-1-trifluoromethylbenzene 

Downstream Products

• 634464-99-6 N-[1-benzyl-4-[3-trifluoromethyl-phenyl]-piperidin-4-yl]acetamide 
• 1683-23-4 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridinium chloride 
• 346688-68-4 1-benzyl-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine 
• 6652-16-0 4-(3-trifluoromethyl-phenyl)-piperidine hydrochloride 

Relevant articles and documents

Synthesis and SAR study of 4-arylpiperidines and 4-aryl-1,2,3,6- tetrahydropyridines as 5-HT2C agonists

A series of substituted 4-arylpiperidines and a smaller family of 4-aryl-1,2,3,6-tetrahydropyridines were synthesized and their biological activity at the 5-HT2C receptor studied to determine whether either series showed noteworthy agonist activity. Structure-activity relationships were developed from the performed receptor binding assays and functional studies, and the results of the analysis are presented herein.

Modulators of dopamine neurotransmission

A 3-substituted 4-(phenyl-N-alkyl)-piperazine compound of the following formula: wherein R1 is selected from the group consisting of OSO2CF3, OSO2CH3, SO2R3, COCF3, CO