561314-57-6

Basic information

• Product Name: 2,8-DIAZASPIRO[4.5]DECAN-3-ONE
• Synonyms: 2,8-DIAZASPIRO[4.5]DECAN-3-ONE;2,8-Diazaspiro[4.5]decan-...;2,8-diazaspiro[4.5]decan-3-one(SALTDATA: 2HCl);3,8-Diazaspiro[4.5]decan-2-one HCl
• CAS NO: 561314-57-6
• Molecular Formula: C₈H₁₄N₂O
• Molecular Weight: 154.20956
• Mol File: 561314-57-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 360.137 °C at 760 mmHg
• Flash Point: 170.81 °C
• Appearance: /
• Density: 1.129 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 16.29±0.20(Predicted)
• CAS DataBase Reference: 2,8-DIAZASPIRO[4.5]DECAN-3-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,8-DIAZASPIRO[4.5]DECAN-3-ONE(561314-57-6)
• EPA Substance Registry System: 2,8-DIAZASPIRO[4.5]DECAN-3-ONE(561314-57-6)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 561314-57-6(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C8H14N2O/c11-7-5-8(6-10-7)1-3-9-4-2-8/h9H,1-6H2,(H,10,11)

Upstream product

• 1462385-41-6 4-(2-ethoxy-2-oxoethyl)-4-(nitromethyl)piperidine-1-formic acid tert-butyl ester 
• 135716-08-4 tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 169206-67-1 3-oxo-2,8-diazaspiro<4.5>decane-8-carboxylic acid tert-butyl ester 
• 945892-88-6 2,8-diazaspiro[4.5]decan-3-one hydrochloride 

Relevant articles and documents

Spiro aryl phosphorus oxide or sulfide

The invention discloses a spiro aryl phosphorus oxide or sulfide as ALK inhibitor, and in particular discloses a compound shown in a formula (I) as an ALK inhibitor or a pharmaceutically acceptable salt thereof.

SUBSTITUTED QUINOLONES III

The invention relates to substituted quinolones and to methods for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.