56137-58-7Relevant academic research and scientific papers
Selective C-H bond hydroxylation of cyclohexanes in water by supramolecular control
Yang, Bin,Cui, Jian-Fang,Wong, Man Kin
, p. 30886 - 30893 (2017/07/07)
A new approach for selective hydroxylation of non-activated cyclohexanes using dioxirane generated in situ in water through supramolecular control has been developed. Using β-CD and γ-CD as the supramolecular hosts, selective hydroxylation of cyclohexane substrates, including trans/cis-1,4-, 1,3-and 1,2-dimethylcyclohexanes and trans/cis-decahydronaphthalene, was achieved in up to 54% yield in water. Furthermore, site-selective C-H bond hydroxylation of (+)-menthol was achieved by obstructing the approach of dioxirane to the C-H bond with higher steric hindrance through inclusion complexation with β-CD and γ-CD in water.
Stereoselective dioxirane hydroxylations and the synthesis of tripod boronic acid esters
D'Accolti, Lucia,Fiorentino, Michele,Fusco, Caterina,Capitelli, Francesco,Curci, Ruggero
, p. 3575 - 3578 (2007/10/03)
Methyl(trifluoromethyl)dioxirane (TFDO, 1b), a powerful yet selective oxidant, was employed to achieve in high yield the direct stereoselective hydroxylation at tert-CH of cis,cis-1,3,5-trimethylcyclohexane (4), yielding triol 7 bearing all-axial disposit
