56138-36-4Relevant academic research and scientific papers
Ligand-dependent site-selective suzuki cross-coupling of 3,5-dichloropyridazines
Dai, Xing,Chen, Yonggang,Garrell, Stephanie,Liu, Hong,Zhang, Li-Kang,Palani, Anandan,Hughes, Gregory,Nargund, Ravi
, p. 7758 - 7763 (2013/09/02)
General methods for the highly site-selective Suzuki monocoupling of 3,5-dichloropyridazines have been discovered. By changing the ligand employed, the preferred coupling site can be switched from the 3-position to the 5-position, typically considered the less reactive C-X bond. These conditions are applicable to the coupling of a wide variety of aryl-, heteroaryl-, and vinylboronic acids with high selectivities, thus enabling the rapid construction of diverse arrays of diarylpyradazines in a modular fashion.
PYRIDAZINE DERIVATIVES FROM ACYCLIC ENAMINES. CHAIN-RING TAUTOMERIC AND EPIMERIC EQUILIBRIUM IN 6-HYDROXY-1,4,5,6-TETRAHYDROPYRIDAZINES
Cocco, Maria Teresa,Congiu, Cenzo,Maccioni, Antonio,Plumitallo, Antonio
, p. 187 - 192 (2007/10/02)
The reaction between ω-bromoacetophenone semicarbazone and various morpholino-enamines of aldehydes and acyclic ketones have been studied.With the enamines of the aldehydes, the reaction leads to the exclusive formation of 6-amino-1,4,5,6-tetrahydropyrida
