56157-07-4

Upstream product

• 536-38-9 4-chlorobenzoylmethyl bromide 
• 640-61-9 N-methyl-p-toluenesulfonylamide 
• 22479-32-9 1-(4-chlorophenyl)vinyl acetate 

Downstream Products

• 1427206-72-1 C₁₇H₁₆ClNO₅S 
• 1427206-67-4 C₁₆H₁₆ClNO₃S 

Relevant academic research and scientific papers

Visible-Light-Mediated Amination of π-Nucleophiles with N-Aminopyridinium Salts

N-Aminopyridinium salts generate nitrogen-centered radicals by means of photoredox catalysis. Herein, we report that they can be trapped by enol equivalents to give α-amino carbonyl compounds in excellent yields. The broad synthetic utility of this method is demonstrated by functionalization of ketones, aldehydes, esters enol equivalents, vinyl ethers, and 1,3-diketones without the need for prior conversion to enol derivatives. The developed method is easily scalable, offers broad substrate scope, high chemoselectivity.

CHEMICAL COMPOUNDS

Compounds of formula (I):wherein variable groups are as defined within; for use in the inhibition of 11betaHSD1 are described