56157-92-7 Usage
Uses
Used in Pharmaceutical and Agrochemical Industries:
4-chloro-2-methylbenzenesulfonyl chloride is used as a reagent for the preparation of various pharmaceutical and agrochemical products. Its strong electrophilic nature makes it suitable for use in the synthesis of these products, contributing to their development and effectiveness.
Used in Medicinal Chemistry and Drug Discovery:
In the field of medicinal chemistry, 4-chloro-2-methylbenzenesulfonyl chloride is utilized as a building block in the synthesis of new compounds with potential therapeutic applications. Its versatile nature allows for the exploration of novel drug candidates and the advancement of drug discovery efforts.
Used in Specialty Chemicals Production:
4-chloro-2-methylbenzenesulfonyl chloride also finds applications in the production of specialty chemicals. Its unique properties and reactivity make it a valuable component in the synthesis of various specialty chemicals, contributing to the development of innovative products and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 56157-92-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,1,5 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 56157-92:
(7*5)+(6*6)+(5*1)+(4*5)+(3*7)+(2*9)+(1*2)=137
137 % 10 = 7
So 56157-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H6Cl2O2S/c1-5-4-6(8)2-3-7(5)12(9,10)11/h2-4H,1H3
56157-92-7Relevant academic research and scientific papers
Synthesis of 3,4-dihydro-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxides and their evaluation as ligands for NMDA receptor glycine binding site
Bluke, Zanda,Paass, Einars,Sladek, Meik,Abel, Ulrich,Kauss, Valerjans
, p. 664 - 673 (2016/05/09)
A series of 2-substituted 3,4-dihydro-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxides were synthesized and evaluated for their affinity to the glycine binding site of the N-methyl-d-aspartate (NMDA) receptor. The binding affinity was determined by the displacement of radioligand [3H]MDL-105,519 from rat cortical membrane preparations. The most attractive structures in the search for prospective NMDA receptor ligands were identified to be 2-arylcarbonylmethyl substituted 3,4-dihydro-2H-1,2-benzothiazine-3-carboxylic acid 1,1-dioxides. It has been demonstrated for the first time that the replacement of NH group in the ligand by sp3 CH2 is tolerated. This finding may pave the way for previously unexplored approaches for designing new ligands of the NMDA receptor.
THIOPHENE-2-CARBOXAMIDE DERIVATIVES AS MODULATORS OF CCR9 RECEPTOR
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Page/Page column 52-53, (2009/05/29)
Provided are compounds of Formula (I) or of Formula (II) that are modulators of CCR9 receptor activity, compositions containing the compounds and methods of use of the compounds and compositions. In certain embodiments, provided are methods for treating or amelioratin diseases associated with modulation of CCR9 receptor activity.
