56160-71-5Relevant academic research and scientific papers
On the stereoselective bicyclization of aminodienes catalyzed by chelating diamide complexes of the group 3 metals. A direct comparison of Sc(iii) and Y(iii) bis(amide)s with an application to the synthesis of alkaloid 195F
Jiang, Tao,Livinghouse, Tom,Lovick, Helena M.
, p. 12861 - 12863 (2012/02/02)
Highly diastereoselective bicyclizations of aminodienes catalyzed by chelating diamide complexes of Sc(iii) and Y(iii) that lead to pyrrolizidines and indolizidines are described. This bis(annulation) procedure has been utilized in a concise synthesis of the pyrrolizidine alkaloid 195F.
Highly efficient, base-catalysed, intramolecular hydroamination of non-activated olefins
Quinet, Coralie,Jourdain, Pierre,Hermans, Christophe,Ates, Ali,Lucas, Isabelle,Markó, István E.
, p. 1077 - 1087 (2008/09/17)
The intramolecular hydroamination of a large variety of non-activated alkenes can be efficiently catalysed by small amounts of lithium bases, providing smoothly and in high yields the corresponding five- and six-membered ring heterocycles. Fused and bridged bicyclic amines, of varying ring sizes, can be readily prepared either by a sequential hydroamination process or by a tandem, double addition reaction.
Chelating diamide based rate enhancement of intramolecular alkene hydroaminations catalyzed by a neutral Sc(III) complex
Joon, Young Kim,Livinghouse, Tom
, p. 4391 - 4393 (2007/10/03)
(Chemical Equation Presented) Neutral scandium amido complexes are viable catalysts for intramolecular alkene hydroamination. Catalytic activity is strongly coupled to the electronic character of the Sc(III) ligand environment with chelating diamide coord
Intramolecular alkene hydroaminations catalyzed by simple amido derivatives of the Group 3 metals
Kim, Young Kwan,Livinghouse, Tom,Bercaw, John E.
, p. 2933 - 2935 (2007/10/03)
Bis(trimethylsilyl) amides of the type Ln[N(TMS) 2]3 have been found to be competent catalysts for representative intramolecular alkene hydroaminations. The catalytic cyclization of an aminodiene proceeds in a stepwise manner to provide the corresponding monocycle and bicycle in a highly stereocontrolled manner.
Reverse Cope Elimination Reactions. 2. Application to Synthesis
Ciganek, Engelbert
, p. 5803 - 5807 (2007/10/03)
Intramolecular addition of N,N-disubstituted hydroxylamines to unactivated olefins was used to prepare an indolizine, a pyrroloisoquinoline, a 1,8-diazaspirodecane, a cyclopentapyrrole, and an isoindoline.A pyrrolizine and a 1-azabicyclo2.
