5621-58-9Relevant academic research and scientific papers
Substituted tetramethylene such neuraminidase inhibitor and method of use thereof, and use thereof
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Paragraph 0180; 0181, (2017/02/28)
The invention provides a novel substituted-cyclobutane compound or a stereoisomer, a tautomer, nitrogen oxide, a solvate, a metabolite, a pharmaceutically-acceptable salt or a prodrug of the novel substituted-cyclobutane compound, wherein the novel substituted-cyclobutane compound is used for inhibiting neuraminidase. The invention also provides a pharmaceutical composition containing the compound and a method for preventing or treating viral infectious diseases by using the compound or the pharmaceutical composition provided by the invention.
Chemoselective hydrogenation of α,β-unsaturated aldehydes with modified Pd/C catalyst
Du, Wen Qiang,Rong, Ze Ming,Liang, Yan,Wang, Yong,Lu, Xin Yi,Wang, Yi Fan,Lu, Lian Hai
experimental part, p. 773 - 776 (2012/08/14)
Selective hydrogenation of α,β-unsaturated aldehydes with modified Pd/C catalyst was developed. The reduction of CO bond could be efficiently inhibited by the addition of carbonates, and high selectivity to the corresponding saturated aldehydes was achieved under mild conditions. This protocol provides an alternative for efficient preparation of saturated aldehydes.
