5624-04-4Relevant articles and documents
Ribosides and Ribotide of a Fairy Chemical, Imidazole-4-carboxamide, as Its Metabolites in Rice
Choi, Jae-Hoon,Matsuzaki, Nobuo,Wu, Jing,Kotajima, Mihaya,Hirai, Hirofumi,Kondo, Mitsuru,Asakawa, Tomohiro,Inai, Makoto,Ouchi, Hitoshi,Kan, Toshiyuki,Kawagishi, Hirokazu
, p. 7841 - 7845 (2019)
The metabolism of imidazole-4-carboxamide (ICA) in plants has been unknown. Two metabolites (1 and 2) were isolated from ICA-treated rice, and their structures were determined by spectroscopic analysis including the single-crystal X-ray diffraction technique and synthesis. The ribotide of ICA (3), whose existence was predicted, was also synthesized and detected from the treated rice by LC-MS/MS. These results indicated that rice might interconvert ICA, 1, and 3 to regulate the biological activity.