56242-67-2 Usage
Description
(4,5-DIHYDRO-THIAZOL-2-YL)-(4-METHOXY-PHENYL)-AMINE, also known as DHMT, is a chemical compound characterized by its molecular formula C11H13N3OS. It is a thiazole derivative featuring a substituted phenylamine group. DHMT is recognized for its potential applications in organic synthesis and pharmaceutical research, where it can serve as a building block for the development of biologically active compounds and drug candidates. Its unique structural properties and reactivity make it a promising tool for creating new therapeutic agents and chemical probes for various biological studies.
Uses
Used in Pharmaceutical Research:
DHMT is used as a key intermediate in the synthesis of various biologically active compounds, contributing to the development of novel drug candidates. Its structural versatility and reactivity enable the creation of a wide range of therapeutic agents with potential applications in treating different medical conditions.
Used in Organic Synthesis:
In the field of organic synthesis, DHMT serves as a valuable building block for constructing complex molecular structures. Its unique properties facilitate the development of new chemical entities with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Drug Development:
DHMT's potential in drug development lies in its ability to be incorporated into the design of new therapeutic agents. Its structural features and reactivity make it an attractive candidate for the creation of compounds with improved pharmacological properties, such as enhanced potency, selectivity, and bioavailability.
Used in Chemical Probes for Biological Studies:
DHMT can be utilized as a chemical probe to investigate various biological processes and pathways. Its unique structural properties allow for the development of targeted molecular tools that can help researchers gain a deeper understanding of complex biological systems and identify potential therapeutic targets for drug discovery.
Further research is necessary to fully explore and harness the potential of DHMT in these and other scientific and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 56242-67-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,2,4 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 56242-67:
(7*5)+(6*6)+(5*2)+(4*4)+(3*2)+(2*6)+(1*7)=122
122 % 10 = 2
So 56242-67-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N2OS/c1-13-9-4-2-8(3-5-9)12-10-11-6-7-14-10/h2-5H,6-7H2,1H3,(H,11,12)
56242-67-2Relevant articles and documents
Synthesis and QSAR studies in 2-(N-aryl-N-aroyl)amino-4,5-dihydrothiazole derivatives as potential antithrombotic agents
Saxena, Anil K.,Pandey, Suresh K.,Seth,Singh,Dikshit,Carpy
, p. 2025 - 2034 (2007/10/03)
A series of 2-(N-aryl-N-aroyl)amino-4,5-dihydrothiazole derivatives have been synthesized via cyclocondensation of N-aryl thioureas with 2-bromoethylamine hydrobromide followed by the reaction of the product thus obtained with aroyl chlorides. Title compounds were evaluated for their antithrombotic activity in vivo in mice where one of these compound 29 provided 65% protection as compared to 77% protection offered by the standard Indomethacin. Quantitative Structure-Activity Relationship (QSAR) studies were performed on these compounds using physicochemical (hydrophobic, electronic, steric) parameter as independent and antithrombic activity as dependent parameter, where antithrombotic activity correlated best (r > 0.8) with electronic parameters (F, σ or μ) having high statistical significance > 99.9% (F2,22 > 15.0; F2,22α:0.001 = 11.0) suggesting that hydrophobic, steric and resonance factors are insignificant in this set of molecules for the activity.
