5625-93-4 Usage
Uses
Used in Pharmaceutical Industry:
4-(1-piperazinylsulfonyl)morpholine (SALTDATA: HCl) is used as a pharmaceutical intermediate for its ability to form stable salts with various acids, which is crucial in the development of new drugs and medicines. This property enhances the solubility and bioavailability of active pharmaceutical ingredients, thereby improving their therapeutic efficacy.
Used in Organic Synthesis:
In the field of organic synthesis, 4-(1-piperazinylsulfonyl)morpholine (SALTDATA: HCl) serves as a valuable reagent. Its unique chemical properties allow it to participate in a variety of chemical reactions, contributing to the synthesis of complex organic compounds and facilitating the creation of novel pharmaceutical agents.
Used in Medical Research:
4-(1-piperazinylsulfonyl)morpholine (SALTDATA: HCl) is utilized in medical research for its potential applications in various areas. Its unique structural characteristics make it a candidate for exploring new therapeutic approaches and understanding the mechanisms of action in different diseases.
Overall, 4-(1-piperazinylsulfonyl)morpholine (SALTDATA: HCl) is a versatile chemical compound with significant applications across the pharmaceutical industry, organic synthesis, and medical research, highlighting its importance in the development of innovative treatments and therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 5625-93-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,2 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5625-93:
(6*5)+(5*6)+(4*2)+(3*5)+(2*9)+(1*3)=104
104 % 10 = 4
So 5625-93-4 is a valid CAS Registry Number.
5625-93-4Relevant academic research and scientific papers
Discovery of Novel Chromone Derivatives Containing a Sulfonamide Moiety as Anti-ToCV Agents through the Tomato Chlorosis Virus Coat Protein-Oriented Screening Method
Jiang, Donghao,Chen, Jixiang,Zan, Ningning,Li, Chunyi,Hu, Deyu,Song, Baoan
, p. 12126 - 12134 (2021/10/26)
A number of novel chromone derivatives containing sulfonamide moieties were designed and synthesized, and the activity of compounds against tomato chlorosis virus (ToCV) was assessed using the ToCVCP-oriented screening method. Comparative molecular field analysis (CoMFA) and comparative molecular similarity index analysis (CoMSIA) models were established based on the dissociation constant (Kd) values of the target compounds, and compound 35 was designed and synthesized with the aid of CoMFA and CoMSIA models. The study of affinity interaction indicated that compound 35 exhibited excellent affinity with ToCVCP with a Kd value of 0.11 μM, which was better than that of the positive control agents xiangcaoliusuobingmi (0.44 μM) and ningnanmycin (0.79 μM). In addition, the in vivo inhibitory effect of compound 35 on the ToCVCP gene was evaluated by the quantitative real-time polymerase chain reaction. ToCVCP gene expression levels of the compound 35 treatment group were reduced by 67.2%, which was better than that of the positive control agent ningnanmycin (59.5%). Therefore, compound 35 can be used as a potential anti-ToCV drug in the future.
