562803-63-8Relevant academic research and scientific papers
Suzuki-miyaura cross-coupling of potassium trifluoro(N -methylheteroaryl) borates with aryl and heteroaryl halides
Molander, Gary A.,Ryu, Daweon,Hosseini-Sarvari, Mona,Devulapally, Rammohan,Seapy, Dave G.
, p. 6648 - 6656 (2013/07/26)
The synthesis of potassium trifluoro(N-methylheteroaryl)borates and their use in cross-coupling reactions with various aryl and heteroaryl halides to construct N-methyl heteroaryl-substituted aromatic and heteroaromatic compounds are reported.
A structure-Permeability study of small drug-like molecules
Fichert, Thomas,Yazdanian, Mehran,Proudfoot, John R.
, p. 719 - 722 (2007/10/03)
A systematic structure-permeability relationship study on a set of small drug-like molecules with log D values in the range -2.5 to 3 and carrying a diverse array of functionality reveals that the compounds with log D>0 and 3 are highly permeable. Surprisingly, several tetrazole derivatives were found to be substrates for efflux pump(s).
