56291-50-0Relevant academic research and scientific papers
Diastereoselective synthesis of 3-fluoro-2-substituted piperidines and pyrrolidines
Gichuhi, Paul N.,Kuriyama, Masami,Onomura, Osamu
, p. 331 - 346 (2014/01/17)
A facile procedure for synthesis of trans-3-fluoro-2-substituted piperidines by utilizing electrophilic fluorination of cyclic enamines and Lewis acid mediated nucleophilic substitution has been developed. Also, optically active trans-2-allyl-3-fluorinate
Efficient synthesis of substituted imidazo[4,5-b] pyridine
Xing, Yuan-Yuan,Liu, Chuanxiang,Wu, Fanhong
, p. 327 - 330 (2014/01/06)
An efficient approach to the synthesis of 1-methylimidazo[4,5-b]pyridine derivatives 5-10 of biological interest has been developed. The key intermediate product 4 is obtained by cyclization of 2-amino-3-methylaminopyridine (3) with phenylacetic acid.
