563-04-2

Usage

Uses

Used in Chemical Industry:
TRI-M-TOLYL PHOSPHATE is used as a chemical intermediate for the synthesis of various compounds and materials. Its versatile chemical properties make it suitable for use in the production of plastics, resins, and other polymers.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TRI-M-TOLYL PHOSPHATE is used as a component in the formulation of certain drugs. Its stability and compatibility with other ingredients make it a valuable addition to the development of new medications.
Used in Agriculture:
TRI-M-TOLYL PHOSPHATE is employed as an additive in the agricultural sector, particularly in the production of pesticides and herbicides. Its ability to enhance the effectiveness of these chemicals while minimizing their environmental impact makes it a valuable asset in this industry.
Used in Lubricant Industry:
TRI-M-TOLYL PHOSPHATE is used as a lubricant additive, providing improved performance and reduced friction in various mechanical applications. Its compatibility with a wide range of materials and its ability to withstand high temperatures make it an ideal choice for use in the lubricant industry.
Used in Flame Retardant Industry:
In the flame retardant industry, TRI-M-TOLYL PHOSPHATE is used as an additive to enhance the fire-resistant properties of materials. Its ability to slow down the spread of flames and reduce the heat release rate makes it a valuable component in the development of safer materials for various applications.

Air & Water Reactions

May hydrolyze under alkaline conditions. . Insoluble in water.

Reactivity Profile

Organophosphates, such as TRI-M-TOLYL PHOSPHATE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

InChI:InChI=1/C21H21O4P/c1-16-7-4-10-19(13-16)23-26(22,24-20-11-5-8-17(2)14-20)25-21-12-6-9-18(3)15-21/h4-15H,1-3H3

Upstream product

• 108-39-4 3-methyl-phenol 
• 3019-89-4 sodium 3-methylphenoxide 
• 620-38-2 tri-m-tolyl phosphite 

Downstream Products

• 36400-46-1 Phosphorsaeure-di-m-tolylester 
• 127580-00-1 phosphoric acid tris-(4-bromo-3-methyl-phenyl ester) 
• 7025-91-4 4-m-tolylmorpholine 
• 210162-62-2 1-(3-methylphenyl)-1H-indole 
• 2581-34-2 3-methyl-4-nitrophenol 
• 700-38-9 2-nitro-5-methylphenol 

Relevant academic research and scientific papers

Diphenyl Diselenide-Catalyzed Synthesis of Triaryl Phosphites and Triaryl Phosphates from White Phosphorus

Industrially important triaryl phosphites, traditionally prepared from PCl3, have been synthesized by a diphenyl diselenide-catalyzed one-step procedure involving white phosphorus and phenols, which provides a halogen- and transition metal-free way to these compounds. Subsequent oxidation of triaryl phosphites produces triaryl phosphates and triaryl thiophosphates. Phosphorotrithioates are also prepared efficiently from aromatic thiols and aliphatic thiols.

Nickel-catalyzed amination of aryl phosphates through cleaving aryl C-O bonds

The amination of triaryl phosphates was achieved using a Ni(II)-(σ-Aryl) complex/NHC catalyst system in dioxane at 110 °C in the presence of NaH as base. Electron-neutral, -rich, and -deficient triaryl phosphates were coupled with a wider range of amine partners including cyclic and acyclic secondary amines, aliphatic primary amines, and anilines in good to excellent yields.

Absolute viscosity and density of trisubstituted phosphoric esters

This paper presents measurements on the absolute viscosity (η) and density (ρ) of trisubstituted phosphoric esters which are useful in understanding their flow mechanism necessary for accessing their role as plasticizers. The effect of chain length and branching has been examined on the η and ρ trends. From η data, by using the Vogel-Tammann-Fulchur (VTF) equation, the VTF temperature (To) has been obtained which also represents the ideal glass transition temperature. To is related to the flexibility of the molecules. It is observed that To initially decreases with molecular weight, reaches a minimum, and increases thereafter. The initial decrease in To has been attributed to the enhanced flexibility of the phosphate esters. Reversal of flexibility with relative molar mass beyond 400 is due to the gentle collision of the arms of the trisubstituted phosphoric esters. This has been further corroborated from the molar mass exponent as exhibited in the η-molar mass plot. The isomeric effect on η has also been investigated in tricresyl phosphates, hitherto for the first time. The ortho isomer has highest η among the isomers. The para isomer was found to have lowest To and hence highest flexibility compared to the ortho and meta isomers.

Polymer supported reagents: An efficiant and simple method for the synthesis of triaryl phosphates

The reaction of phosphoryl chloride with insoluble polymer-supported phenoxide ion reagents in benzene at room temperature, produced triaryl phosphates in excellent yields. The isolation of pure products by simple filtration and evaporation is an important feature of this method.

Metalation-Induced Double Migration of Phosphorus from O-->C. Convenient Preparation of Bis(2-hydroxyaryl)phosphinic Acids

Treatment of diaryl ethyl phosphates 8 with lithium diisopropylamide in tetrahydrofuran yields ethyl bis(2-hydroxyaryl)phosphinates 9.The reaction involves the double migration of phophorus from O-->C and is probably intramolecular.These phosphinate esters 9 on treatment with trimethylsilyl chloride and sodium iodide in acetonitrile undergo transesterification to give trimethylsilyl esters that yield the corresponding phosphinic acids 15 on treatment with water.