56304-75-7

Usage

Uses

Used in Pharmaceutical Industry:
3-Cyano-6-(2-furanyl)-2-hydroxypyridine is used as a building block for the synthesis of various biologically active molecules, contributing to the development of new drugs and agrochemicals.
Used in Organic Synthesis:
3-Cyano-6-(2-furanyl)-2-hydroxypyridine is used as a reagent in organic synthesis, facilitating the creation of complex organic compounds and aiding in various chemical reactions.
Used in Scientific Research:
3-Cyano-6-(2-furanyl)-2-hydroxypyridine serves as a research tool in various scientific studies, providing insights into chemical behavior and potential applications in different fields.
Used in Drug Development:
3-Cyano-6-(2-furanyl)-2-hydroxypyridine is used in the development of new drugs, leveraging its versatile chemical properties to create innovative pharmaceutical compounds.
It is important to handle and store 3-Cyano-6-(2-furanyl)-2-hydroxypyridine with proper safety measures due to its chemical nature to prevent any potential hazards.

InChI:InChI=1/C10H6N2O2/c11-6-7-3-4-8(12-10(7)13)9-2-1-5-14-9/h1-5H,(H,12,13)

Upstream product

• 17168-45-5 3-(dimethylamino)-1-(furan-2-yl)-2-propen-1-one 
• 107-91-5 cyanoacetic acid amide 
• 109482-86-2 (2E)-3-(dimethylamino)-1-furan-2-ylprop-2-en-1-one 
• 1174035-51-8 2-cyano-5-dimethylamino-5-furan-2-yl-penta-2,4-dienoic acid amide 
• 1192-62-7 1-(2-furyl)-1-ethanone 

Relevant academic research and scientific papers

Discovery and structure-activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors

Current treatment for hepatitis C is barely satisfactory, there is an urgent need to develop novel agents for combating hepatitis C virus infection. This study discovered a new class of thieno[2,3-b]pyridine derivatives as HCV inhibitors. First, a hit compound characterized by a thienopyridine core was identified in a cell-based screening of our privileged small molecule library. And then, structure activity relationship study of the hit compound led to the discovery of several potent compounds without obvious cytotoxicity in vitro (12c, EC50 = 3.3 μM, SI >30.3, 12b, EC50 = 3.5 μM, SI >28.6, 10l, EC50 = 3.9 μM, SI >25.6, 12o, EC 50 = 4.5 μM, SI >22.2, respectively). Although the mechanism of them had not been clearly elucidated, our preliminary optimization of this class of compounds had provided us a start point to develop new anti-HCV agents.

Enaminones as building blocks in heterocyclic syntheses: Reinvestigating the product structures of enaminones with malononitrile. A novel route to 6-substituted-3-oxo-2,3-dihydropyridazine-4-carboxylic acids

The reported structures of reaction products of enaminones with malononitrile in ethanolic piperidine are revised. A novel route to 2,3-dihydropyridazine-4-carboxylic acids 4a-c via reactions of 2-cyano-5-(dimethylamino)-5-arylpenta-2,4-dienamides 8a-c wi

About the reaction of β-dimethylamino-α,β-enones with active methylene nitriles

(Chemical Equation Presented) The reaction of 3-dimethylamino-1- arylpropenone derivatives with active methylene nitriles was reinvestigated and a plausible mechanism to account for the results is suggested. X-ray crystallographic study supported the sugg

2-Aminopyridine compounds and use thereof as drugs

The present invention provides 2-aminopyridine compound having an excellent adenosine receptor (A1, A2a, A2b receptors) antagonism, which is represented by the following formula: (wherein, R1 represents cyano gr

2-AMINOPYRIDINE COMPOUNDS AND USE THEREOF AS DRUGS

The present invention provides 2-aminopyridine compound having an excellent adenosine receptor (A1, A2a, A2b receptors) antagonism, which is represented by the following formula: (wherein, R1 represents cyano gr

Substituted N-(1,2-dihydro-2-oxonicotinyl)-cephalexins and -cephaloglycins

Novel organic amide compounds which are substituted N-(1,2-dihydro-2-oxonicotinyl)-ampicillins, -cephalexins and -cephaloglycins having broad spectrum antibacterial utility are provided by (a) reacting the free amino acid ampicillin, cephalexin or cephaloglycin or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding 1,2-dihydro-2-oxonicotinic acid or (b) reacting the free amino acid 6-aminopenicillanic acid, 7-aminocephalosporanic acid or 7-amino-3-methylceph-3-em-4-carboxylic acid or the acid salt or silylated derivative thereof with a reactive derivative of the corresponding N-(1,2-dihydro-2-oxonicotinyl)-2-phenylglycine.