56331-52-3

Basic information

• Product Name: 2-chloro-3-cyano-4-methyl-6-(3'-methoxypropylamino)-pyridine
• Synonyms: 2-chloro-3-cyano-4-methyl-6-(3'-methoxypropylamino)-pyridine
• CAS NO: 56331-52-3
• Molecular Weight: 239.705
• Mol File: 56331-52-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-chloro-3-cyano-4-methyl-6-(3'-methoxypropylamino)-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-cyano-4-methyl-6-(3'-methoxypropylamino)-pyridine(56331-52-3)
• EPA Substance Registry System: 2-chloro-3-cyano-4-methyl-6-(3'-methoxypropylamino)-pyridine(56331-52-3)

Safety Data

• Hazardous Substances Data: 56331-52-3(Hazardous Substances Data)

Upstream product

• 5444-02-0 3-cyano-4-methyl-6-hydroxypyrid-2-one 
• 875-35-4 2,6-dichloro-4-methylnicotinonitrile 
• 5332-73-0 3-methoxypropylamine 

Downstream Products

• 51560-72-6 2,6-bis-(3'-methoxy-n-propylamino)-3-cyano-4-methylpyridine 

Relevant articles and documents

Preparation method for nitrobenzisothiazole-pyridine dye with good acid-base stability

The invention discloses a preparation method for a nitrobenzisothiazole-pyridine dye with good acid-base stability. The preparation method comprises the following steps: (1) preparing a compound (i) from 1,4-dimethyl-3-cyano-6-hydroxy-2-pyridone and phosphorus oxychloride; (2) preparing a compound (ii) from the compound (i) and NH2-(CH2)n-O-CH3; (3) preparing a compound (A) from the compound (ii)and NH2-(CH2)n-O-CH3; (4) diazotizing 3-amino-5-nitrobenzoisothiazole by using sodium nitrite so as to obtain diazonium salt; (5) mixing the diazonium salt with the compound (A) for a reaction, and carrying out aging so as to obtain a crude product; and (6) dissolving the crude product, carrying out cooling extraction, and carrying out purifying so as to obtain a compound as shown in a structuralformula (B) which is described in the specification. According to the invention, the nitrobenzisothiazole-pyridine dye with good acid-base stability is synthesized in a functional group conversion mode; and the preparation method provided by the invention is easily-controllable in reaction conditions, simple in operation and high in product yield.

Process of preparing diaminopyridine compounds

A process for preparing diaminopyridines of the formula STR1 where one of the two radicals X1 and X2 is hydrogen, C1 -C4 -alkyl, halogen or nitro and the other is cyano, R1 is hydrogen, C1 -C4 -alkyl or phenyl, R2 and R3 are each hydrogen, C1 -C4 -alkyl or C1 -C4 -alkoxy, R4 is hydrogen or C1 -C4 -alkyl, and R5 is optionally substituted C1 -C10 -alkyl, C3 -C4 -alkenyl or C5 -C7 -cycloalkyl, by reacting dichloropyridines of the formula STR2 in a first step with an amine of the formula R5 -NH2 at from 10° to 80° C. in the presence of a base and of an inert organic diluent and/or water, then removing the diluent and thereafter, with or without prior intermediate isolation of the reaction product, comprises carrying out the second step in a melt at from 90° to 165° C. and at a pH from 3.5 to 6.5 using from 1.3 to 3 mol of aniline IV are used per mole of dichloropyridine II.