56335-71-8

Basic information

• Product Name: 1-(3-Ethylcyclobutyl)ethanone
• Synonyms: 1-(3-Ethylcyclobutyl)ethanone
• CAS NO: 56335-71-8
• Molecular Formula: C8H14O
• Molecular Weight: 126.2
• Mol File: 56335-71-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 173.2±8.0 °C(Predicted)
• Appearance: /
• Density: 0.902±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-(3-Ethylcyclobutyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Ethylcyclobutyl)ethanone(56335-71-8)
• EPA Substance Registry System: 1-(3-Ethylcyclobutyl)ethanone(56335-71-8)

Safety Data

• Hazardous Substances Data: 56335-71-8(Hazardous Substances Data)

Upstream product

• 66016-16-8 3-ethylcyclobutane carboxylic acid 
• 917-54-4 methyllithium 

Relevant articles and documents

Preparation of 15-deoxy-16-hydroxyprostaglandins

Analogues of PGE1 having the structural formula, STR1 in which J is R-hydroxymethylene or S-hydroxymethylene; R1 is hydrogen; R2 is hydrogen or together with R4 is a methylene chain of 2 to 3 carbon atoms such that a cycloalkyl of 5 to 6 carbon atoms inclusive is formed; R3 is hydrogen or methyl, or together with R4 is a methylene or a lower alkylated methylene chain of 2 to 5 carbon atoms such that a cycloalkyl or a lower alkylated cycloalkyl of 4 to 7 carbon atoms inclusive is formed, or together with R4 is bicycloalkyl or bicycloalkenyl moiety having the formula: STR2 SUCH THAT A BICYCLOALKYL OR BICYCLOALKENYL COMPOUND IS FORMED, WHEREIN M AND N ARE INTEGERS HAVING A VALUE FROM 0 TO 3, P IS AN INTEGER HAVING A VALUE FROM 0 TO 4 AND Q IS AN INTEGER HAVING A VALUE OF FROM 1 TO 4 AND WHEREIN THE DOUBLE BOND OF SUCH BICYCLOALKENYL IS IN THE M, N, P, OR Q BRIDGE; R4 is hydrogen or methyl or together with R2 or R3 forms a cycloalkyl or bicycloalkyl or bicycloalkenyl as defined above, or together with R5 is a methylene chain of 3 to 5 carbon atoms such that a cycloalkyl of 4 to 6 carbon atoms inclusive is formed; R5 is selected from the group consisting of hydrogen, straight-chain alkyl having from 1 to 3 carbon atoms or together with R4 forms a cycloalkyl as defined above; and R6 is hydrogen or straight-chain alkyl having from 1 to 3 carbon atoms are disclosed. Pge1 ester analogues of the above formula, limited to the structures wherein two of R2, R3 R4 and R5 form a cycloalkyl, lower alkylated cycloalkyl, bicycloalkyl or bicycloalkenyl are also disclosed. The prostaglandin analogues selectively produce bronchodilation and decrease gastric secretion in vivo. Methods of preparing the analogues and starting materials required in the synthesis of the analogues are also disclosed.