56348-66-4 Usage
Uses
Used in Pharmaceutical Industry:
(R)-Benzyl 2-Bromo-3-Phenylpropionate is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicine and healthcare.
Used in Agrochemical Industry:
In the agrochemical sector, (R)-Benzyl 2-Bromo-3-Phenylpropionate is utilized as an intermediate in the production of agrochemicals. Its incorporation into these compounds can lead to the development of more effective and targeted pest control solutions, benefiting agriculture and food production.
Used in Fragrance and Flavor Industry:
(R)-Benzyl 2-Bromo-3-Phenylpropionate is used as a building block in the creation of fragrances and flavors. Its unique chemical properties enable the development of novel scents and tastes, enriching the sensory experiences in various consumer products.
Used in Specialty Chemicals Production:
(R)-BENZYL 2-BROMO-3-PHENYLPROPIONATE also finds application in the production of specialty chemicals, where its versatility and reactivity contribute to the development of innovative and high-performance chemical products for diverse industries.
Check Digit Verification of cas no
The CAS Registry Mumber 56348-66-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,3,4 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 56348-66:
(7*5)+(6*6)+(5*3)+(4*4)+(3*8)+(2*6)+(1*6)=144
144 % 10 = 4
So 56348-66-4 is a valid CAS Registry Number.
56348-66-4Relevant academic research and scientific papers
Cobalt-bisoxazoline-catalyzed asymmetric kumada cross-coupling of racemic α-bromo esters with aryl grignard reagents
Mao, Jianyou,Liu, Feipeng,Wang, Min,Wu, Lin,Zheng, Bing,Liu, Shangzhong,Zhong, Jiangchun,Bian, Qinghua,Walsh, Patrick J.
, p. 17662 - 17668 (2015/02/02)
The first cobalt-catalyzed asymmetric Kumada cross-coupling with high enantioselectivity has been developed. The reaction affords a unique strategy for the enantioselective arylation of α-bromo esters catalyzed by a cobalt-bisoxazoline complex. A variety of chiral α-arylalkanoic esters were prepared in excellent enantioselectivity and yield (up to 97% ee and 96% yield). The arylated products were transformed into α-arylcarboxylic acids and primary alcohols without erosion of ee. The new enantioenriched α-arylpropionic esters synthesized herein are potentially useful in the development of nonsteroidal anti-inflammatory drugs. This method was conducted on gram-scale and applied to the synthesis of highly enantioenriched (S)-fenoprofen and (S)-ar-turmerone.
One-pot synthesis of α-bromoesters and ketones from β-ketoesters and diketones using supported reagents system
Aoyama, Tadashi,Takido, Toshio,Kodomari, Mitsuo
, p. 1873 - 1876 (2007/10/03)
A simple and efficient method has been developed for the synthesis of α-bromoesters and ketones from β-ketoesters and diketones in one pot using a supported reagents system, CuBr2/Al2O 3-Na2CO3/Al2O3, in which β-ketoester reacts first with CuBr2/Al2O3 and the product, α-bromo-β-ketoester, reacts with Na 2CO3/Al2O3 to give the final product, α-bromoesters in good yields.
