56352-95-5

Upstream product

• 56352-81-9 nicotinic acid N'-(4-nitro-benzoyl)-hydrazide 
• 614-18-6 3-pyridinecarboxylic acid ethyl ester 
• 553-53-7 Nicotinic acid hydrazide 
• 62-23-7 4-nitro-benzoic acid 
• 62984-50-3 (E)-N’-(4'-nitrobenzylidene)nicotinohydrazide 

Downstream Products

• 91823-38-0 4-(5-(pyridin-3-yl)-1,3,4-oxadiazol-2-yl)aniline 
• 1316270-36-6 C₂₀H₁₂BrN₇O₂S 
• 1316270-47-9 C₂₀H₁₂N₈O₄S 
• 1316270-49-1 C₂₀H₁₁Cl₂N₇O₂S 
• 1316270-40-2 C₂₁H₁₅N₇O₂S 
• 1316270-44-6 C₂₁H₁₅N₇O₂S 
• 1316270-41-3 C₂₁H₁₅N₇O₃S 
• 1316270-39-9 C₂₀H₁₂N₈O₄S 
• 1316270-34-4 C₂₀H₁₂FN₇O₂S 
• 1316270-43-5 C₂₀H₁₂ClN₇O₂S 
• 1316270-50-4 C₂₀H₁₂ClN₇O₂S 

Relevant academic research and scientific papers

Anti-HIV, antimycobacterial and antimicrobial studies of newly synthesized 1,2,4-triazole clubbed benzothiazoles

In an attempt to synthesize pharmacologically active molecules, we report here the synthesis and in vitro anti-HIV, antimycobacterial and antimicrobial activity of various series of 3-(3-pyridyl)-5-(4-substitutedphenyl)-4-(N- substituted-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole. The anti-HIV activity of the title compounds was evaluated as selective human immunodeficiency virus type-1 and -2 (HIV-1, HIV-2 RT) inhibitors, antitubercular activity against H37Rv using Lowenstein-Jensen agar method and antimicrobial activity against certain bacterial and fungal strains using the broth microdilution method. The synthesized compounds were characterized by FTIR, 1H-NMR,13C-NMR and mass spectral data together with elemental analysis.

Synthesis of 1,2,4-triazole derivatives containing benzothiazoles as pharmacologically active molecule

In attempt to make significant pharmacologically active molecule, we report here the synthesis and in vitro antimicrobial and antitubercular activity of various series of 3-(3-pyridyl)-5-(4-nitrophenyl)-4-(N-substituted-1,3- benzothiazol-2-amino)-4H-1,2,4-triazole. The antimicrobial activity of title compounds were examined against two Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes), two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), and three fungi (Candida albicans, Aspergillus niger, Aspergillus clavatus) using the broth microdilution method and antitubercular activity H37Rv using Lowenstein-Jensen agar method.

Oxidative cyclization of aromatic aldehyde n-acylhydrazones by bis(trifluoroacetoxy)iodobenzene

Aromatic aldehyde N-acylhydrazones were oxidized into 2,5-disubstituted 1,3,4-oxadiazoles with bis(trifluoroacetoxy)iodobenzene in CHCl3 or DMSO at room temperature in good to excellent yields. Copyright Taylor & Francis Group, LLC.